Hypertension is a primary risk factor for cerebral ischemic disease because of its role in the genesis and development of atherosclerotic plaques, in preferencial sites as the carotid bifurcation. Little is known, however, about the relationship between the degree of atheroma and subtypes of hypertension, although actually it seems to be a strong correlation between high values of systolic blood pressure and atheromatous disease. In this study, we have evaluated the prevalence of the carotid artery lesions in 226 hypertensive subjects, aged 66 ± 24 years, admitted in our Institute and categorized in three groups, in consideration of their blood pressure values: isolated systolic hypertension (ISH), mixed hypertension (MH) and isolated diastolic hypertension (IDH). Atheromatous plaques were present especially in subjects of the MH group and of the ISH group. Heterogenous type of plaque and rough plaque surface were predominant. We have also correlated their morphological features with the clinical evidences and we have observed an higher prevalence of ischemic events, major stroke and transient ischemic attacks. Finally, it seems that this study confirms a major association between high values of systolic blood pressure and carotid artery atheroma with risk of cerebral ischemic disease.
|Number of pages||4|
|Journal||Nuova Rivista di Neurologia|
|Publication status||Published - 1998|
ASJC Scopus subject areas
- Clinical Neurology