Cerebral vasculitis in two patients affected by Hodgkin's lymphoma

Sebastiano Gangemi, P. L. Minciullo, L. Morabito, C. Stelitano, V. Callea, G. Penna, F. Morabito

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Granulomatous angiitis of the central nervous system (GACNS) is a rare entity sometimes associated with Hodgkin's lymphoma (HL). Until now, 14 cases of angiitis of CNS associated with HL have been published. Two cases of cerebral vasculitis in patients affected by HL are described. The patients presented an identical clinical outcome, in fact they both were affected by a nodular sclerosis HL, received COPPEBVCAD, presented abdominal sub occlusion, pulmonary embolism and, finally, cerebral vasculitis. Both our patients immediately started vasculitis specific treatment (immunoglobulins and steroids) with substantial improvement in 5 days. The patients both completed chemotherapy protocol, obtaining a complete remission. To our knowledge, this is the first report in which a complete recovery has been described in patients affected by HL and complicated by cerebral vasculitis.

Original languageEnglish
Pages (from-to)119-121
Number of pages3
JournalItalian Journal of Allergy and Clinical Immunology
Issue number3
Publication statusPublished - Sep 2005


  • Angiitis of central nervous system
  • Chemotherapy
  • Hodgkin's lymphoma
  • Vasculitis

ASJC Scopus subject areas

  • Immunology and Allergy


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