Cerebral vein thrombosis and mild hyperhomocysteinemia

Three new cases

A. Rigamonti, M. R. Carriero, G. Boncoraglio, M. Leone, G. Bussone

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Mild hyperhomocysteinemia is an established risk factor for deep vein thrombosis. We report three patients with cerebral vein thrombosis (CVT) in which the only risk factor we were able to identify was increased blood homocysteine levels and the C677T polymorphism in both alleles of the methylene tetrahydrofolate reductase MTHFR gene. We suggest that hyperhomocysteinemia should also be a risk factor for CVT. Since this condition can be effectively and safely corrected by drugs, we suggest that homocysteine levels should be routinely determined in patients with idiopatic CVT, and even mildly increased levels corrected pharmacologically, in the hope of reducing the risks associated with this condition.

Original languageEnglish
Pages (from-to)225-227
Number of pages3
JournalNeurological Sciences
Volume23
Issue number5
DOIs
Publication statusPublished - Dec 2002

Fingerprint

Cerebral Veins
Intracranial Thrombosis
Hyperhomocysteinemia
Homocysteine
Methylenetetrahydrofolate Reductase (NADPH2)
Venous Thrombosis
Alleles
Pharmaceutical Preparations
Genes

Keywords

  • Cerebral vein thrombosis
  • Hyperhomocysteinemia

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Cerebral vein thrombosis and mild hyperhomocysteinemia : Three new cases. / Rigamonti, A.; Carriero, M. R.; Boncoraglio, G.; Leone, M.; Bussone, G.

In: Neurological Sciences, Vol. 23, No. 5, 12.2002, p. 225-227.

Research output: Contribution to journalArticle

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