Cerebral venous thrombosis: A retrospective multicentre study of 48 patients

E. Terazzi, D. Mittino, R. Rudà, P. Cerrato, F. Monaco, R. Sciolla, E. Grasso, M. A. Leone, M. De Mattei, E. Verdun, M. Giraudo, P. Gerbino-Promis, A. Appiotti, P. Gai, E. Bottacchi, C. Labate, A. Villani, E. Pavanelli, G. Ferrari, P. Provera

Research output: Contribution to journalArticlepeer-review

Abstract

The objective was to describe the clinical features and management of cerebral venous thrombosis (CVT) in non-selected centres. An observational study in 11 neurological departments in NW Italy was carried out from 1995 through 1999 on 38 female and 10 male patients. Mean age: 44.8 years, SD=14.3. Onset: acute in 21 patients (44%), subacute in 17 (35%) and chronic in 10 (21%). Most frequent onset: with focal deficits and/or seizures, followed by impaired consciousness or confusion, isolated headache, isolated intracranial hypertension and cavernous syndrome. No risk factor was found in 8 patients (17%). The superior sagittal sinus was involved in 27 patients (56%) and the transverse sinus in 29 (60%). Anticoagulants were used in 45 patients (94%). Rankin Scale score at discharge: 0 (27 patients), 1 (four), 2 (five), 3 (five), 4 (none), 5 (one) and six were dead. Thirteen patients had deep CVT: age, risk factors, neurological signs and outcome differed from cortical CVT (35 patients), although not significantly. Clinical features, risk factors and outcome of CVT patients from non-selected centres are similar to those from specialised centres.

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalNeurological Sciences
Volume25
Issue number6
DOIs
Publication statusPublished - Feb 2005

Keywords

  • Cerebral venous thrombosis
  • Headache
  • Multicentre studies
  • Risk factors
  • Seizures

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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