Abstract
PURPOSE: To evaluate the involvement of central visual pathways in cases of periventricular leukomalacia, and to correlate the neuroradiologic findings with the degree of visual acuity. METHODS: The MR brain examinations of 27 preterm children affected by cerebral palsy resulting from periventricular leukomalacia and without significant ophthalmologic lesions were reviewed retrospectively to search for possible involvement of the optic radiations and/or of the calcarine cortex. The data were compared with the degree of visual acuity estimated by means of the Teller Acuity Cards test. RESULTS: Seventeen (63%) of the 27 patients had cerebral visual impairment, which correlated strongly with ME lesions. Quantitative reduction and signal hyperintensity of the peritrigonal white matter and atrophy of the calcarine cortex were present in the more severe cases. In two blind patients, an altered MR signal was detected in the lateral geniculate bodies. CONCLUSION: This study clearly establishes a relationship between specific MR findings and visual impairment in children with periventricular leukomalacia. The finding of hyperintensity in the lateral geniculate bodies was interpreted as an axonal reaction. MR imaging is useful for detecting potential visual impairment and for improving clinical diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | 979-985 |
| Number of pages | 7 |
| Journal | American Journal of Neuroradiology |
| Volume | 17 |
| Issue number | 5 |
| Publication status | Published - 1996 |
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Keywords
- Brain, magnetic resonance
- Pediatric neuroradiology
- Periventricular leukomalacia
- Vision
ASJC Scopus subject areas
- Clinical Neurology
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
Cerebral visual impairment in periventricular leukomalacia : MR correlation. / Uggetti, Carla; Egitto, Maria Grazia; Fazzi, Elisa; Bianchi, Pier Emilio; Bergamaschi, Roberta; Zappoli, Federico; Sibilla, Luisella; Martelli, Adelaide; Lanzi, Giovanni.
In: American Journal of Neuroradiology, Vol. 17, No. 5, 1996, p. 979-985.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cerebral visual impairment in periventricular leukomalacia
T2 - MR correlation
AU - Uggetti, Carla
AU - Egitto, Maria Grazia
AU - Fazzi, Elisa
AU - Bianchi, Pier Emilio
AU - Bergamaschi, Roberta
AU - Zappoli, Federico
AU - Sibilla, Luisella
AU - Martelli, Adelaide
AU - Lanzi, Giovanni
PY - 1996
Y1 - 1996
N2 - PURPOSE: To evaluate the involvement of central visual pathways in cases of periventricular leukomalacia, and to correlate the neuroradiologic findings with the degree of visual acuity. METHODS: The MR brain examinations of 27 preterm children affected by cerebral palsy resulting from periventricular leukomalacia and without significant ophthalmologic lesions were reviewed retrospectively to search for possible involvement of the optic radiations and/or of the calcarine cortex. The data were compared with the degree of visual acuity estimated by means of the Teller Acuity Cards test. RESULTS: Seventeen (63%) of the 27 patients had cerebral visual impairment, which correlated strongly with ME lesions. Quantitative reduction and signal hyperintensity of the peritrigonal white matter and atrophy of the calcarine cortex were present in the more severe cases. In two blind patients, an altered MR signal was detected in the lateral geniculate bodies. CONCLUSION: This study clearly establishes a relationship between specific MR findings and visual impairment in children with periventricular leukomalacia. The finding of hyperintensity in the lateral geniculate bodies was interpreted as an axonal reaction. MR imaging is useful for detecting potential visual impairment and for improving clinical diagnosis.
AB - PURPOSE: To evaluate the involvement of central visual pathways in cases of periventricular leukomalacia, and to correlate the neuroradiologic findings with the degree of visual acuity. METHODS: The MR brain examinations of 27 preterm children affected by cerebral palsy resulting from periventricular leukomalacia and without significant ophthalmologic lesions were reviewed retrospectively to search for possible involvement of the optic radiations and/or of the calcarine cortex. The data were compared with the degree of visual acuity estimated by means of the Teller Acuity Cards test. RESULTS: Seventeen (63%) of the 27 patients had cerebral visual impairment, which correlated strongly with ME lesions. Quantitative reduction and signal hyperintensity of the peritrigonal white matter and atrophy of the calcarine cortex were present in the more severe cases. In two blind patients, an altered MR signal was detected in the lateral geniculate bodies. CONCLUSION: This study clearly establishes a relationship between specific MR findings and visual impairment in children with periventricular leukomalacia. The finding of hyperintensity in the lateral geniculate bodies was interpreted as an axonal reaction. MR imaging is useful for detecting potential visual impairment and for improving clinical diagnosis.
KW - Brain, magnetic resonance
KW - Pediatric neuroradiology
KW - Periventricular leukomalacia
KW - Vision
UR - http://www.scopus.com/inward/record.url?scp=0029875446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029875446&partnerID=8YFLogxK
M3 - Article
C2 - 8733977
AN - SCOPUS:0029875446
VL - 17
SP - 979
EP - 985
JO - American Journal of Neuroradiology
JF - American Journal of Neuroradiology
SN - 0195-6108
IS - 5
ER -