TY - JOUR
T1 - Cervical carcinoma in young patients
T2 - Clinical and pathological variables
AU - Mariani, L.
AU - Iacovelli, A.
AU - Vincenzoni, C.
AU - Diotallevi, F. F.
AU - Atlante, M.
AU - Lombardi, A.
PY - 1993
Y1 - 1993
N2 - Twenty-five (10.2%) out of 243 untreated patients with invasive cervical carcinoma were 35 years old or younger. When matching the clinical and pathological variables between the younger and the older women, the former were characterized by a higher rate of Stage IB disease (P = 0.10), G3 and G4 tumors (P = 0.25), bulky lesions (P = 0.05) and node metastases (P = 0.50). In spite of this poorer pathological profile, both the 5-year diseasefree survival rate (75%) and survival according to stage of the younger women were similar to those reported in larger series, regardless of the patients' age. No modification of the standard therapy is therefore required in younger patients.
AB - Twenty-five (10.2%) out of 243 untreated patients with invasive cervical carcinoma were 35 years old or younger. When matching the clinical and pathological variables between the younger and the older women, the former were characterized by a higher rate of Stage IB disease (P = 0.10), G3 and G4 tumors (P = 0.25), bulky lesions (P = 0.05) and node metastases (P = 0.50). In spite of this poorer pathological profile, both the 5-year diseasefree survival rate (75%) and survival according to stage of the younger women were similar to those reported in larger series, regardless of the patients' age. No modification of the standard therapy is therefore required in younger patients.
KW - Cervical carcinoma
KW - Prognosis
KW - Young age
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U2 - 10.1016/0020-7292(93)90155-P
DO - 10.1016/0020-7292(93)90155-P
M3 - Article
C2 - 8098297
AN - SCOPUS:0027407202
VL - 41
SP - 61
EP - 66
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
SN - 0020-7292
IS - 1
ER -