Cervical efferent vagal stimulation related or unrelated to cardiac cycles: comparison of negative atrial inotropic effects.

A. Cevese, R. Poltronieri, F. Schena, G. Verlato, C. Zaffagni

Research output: Contribution to journalArticlepeer-review

Abstract

Efferent cervical vagal stimulations were performed in 4 anesthetized dogs, either with trains of stimuli of constant frequency (CONT), or with brief trains, triggered by the atrial electrical activity (TRIG). Heart rate was increased by cardiac pacing during vagal stimulations. Negative inotropic effects of vagal stimulations, evaluated as changes in atrial contractility, were partially inhibited by cardiac acceleration during CONT, but were unaffected during TRIG. It is concluded that the number of stimuli per cycle, not the number of stimuli per second, is the critical factor for parasympathetic heart regulation.

Original languageEnglish
Pages (from-to)2009-2016
Number of pages8
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume60
Issue number11
Publication statusPublished - Nov 30 1984

ASJC Scopus subject areas

  • Medicine(all)

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