Cervical intraepithelial neoplasia with conization: Early complications and follow-up

S. Alberico, M. C. Facca, L. Dal Corso, L. Di Bonito, I. Colautti, R. Casaccia, P. Bogatti, G. P. Mandruzzato

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The authors made a review of the last 100 cases who underwent a conization of the cervix during the period 1980-1986. Cyto-histological evaluation was compatible in 78% of the cases with a cervical intraepithelial neoplasia of third degree and in 22% with a CIN of first and second degree. Early post-operative complications consisted of a hemorrhage in 3% of the cases, easily stopped with a vaginal packing. In 2% of the cases a risuture under general anaesthesia was required. In 1 case the stitches loosened and in another a urinary infection was present. Twenty-six patients underwent total hysterectomy after conization for different indications; only one patient had a relapse after six months as there was a moderate dysplasia localizated in the vaginal vault. During the follow-up, 14 patients became pregnant. Among these, 5 underwent legal termination during the first trimester and 9 delivered at term without any complication. During these follow-up of 7 years in the older cases and 6 months in the more recent ones, 6 cases displayed a persistence of the disease after 3 months, (CIN of variable degree) and 2 cases relapsed at the second colpocytological control. These patients, according to the age and the presence of clinical indications, underwent total hysterectomy or diathermic coagulation with resolution of the disease. A relapsing invasive tumor was never observed.

Original languageEnglish
Pages (from-to)357-362
Number of pages6
JournalEuropean Journal of Gynaecological Oncology
Issue number5
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology


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