Studio osservazionale delle modificazioni della rabbia, depressione, ansia e personalità dopo lobectomia temporale effettuata per epilessia parziale farmacoresistente

Translated title of the contribution: Changes in depression, anxiety, anger, and personality after resective surgery for drug-resistant temporal lobe epilepsy: A 2-year follow-up study

L. G. Grammaldo, A. Picardi, T. Giampà, M. De Risi, P. P. Quarato, C. Di Bonaventura, V. Esposito, G. Di Gennaro

Research output: Contribution to journalArticle

Abstract

Objective: To further elucidate the psychiatric outcome of surgical treatment for temporal lobe epilepsy (TLE). Methods: Fifty-two consecutive patients (70% of all eligible patients) with drug-resistant TLE and IQ ≥ 70 completed the Minnesota Multiphasic Personality Inventory, the Beck Depression Inventory, the Spielberger State-Trait Anxiety Inventory, and the Spielberger State-Trait Anger Expression Inventory before surgical treatment, after one year, and after two years. During the follow-up period, patients were maintained on a stable medication regimen. Repeated measures analysis of variance was used to examine changes in psychiatric variables over time. Results: Seizure outcome was excellent (89% in Engel class I after 2 years). After surgery, the only significant change in personality variables was a decrease in social introversion. Anxiety decreased significantly with a gradual decline, anger dropped significantly after remaining basically flat during the first year, while depression showed a gradual but non-significant decline. Younger age and shorter duration of epilepsy were associated with greater improvement in several anger dimensions. Conclusion: The profile of emotional distress and its relatively slow decrease over time suggest that patients may experience difficulties in switching from a 'sick' role to a 'normal' role and may easily be disappointed if expectations of positive life changes are not rapidly met. Some counselling sessions early after surgery may be useful to address these issues. Surgery may yield greater emotional benefits if performed early.

Original languageItalian
Pages (from-to)207-209
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number136-137
Publication statusPublished - May 2008

Fingerprint

Temporal Lobe Epilepsy
Anger
varespladib methyl
Personality
Anxiety
Depression
Equipment and Supplies
Psychiatry
Sick Role
MMPI
Operative Time
Counseling
Epilepsy
Analysis of Variance
Seizures
Drug Resistant Epilepsy
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

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title = "Studio osservazionale delle modificazioni della rabbia, depressione, ansia e personalit{\`a} dopo lobectomia temporale effettuata per epilessia parziale farmacoresistente",
abstract = "Objective: To further elucidate the psychiatric outcome of surgical treatment for temporal lobe epilepsy (TLE). Methods: Fifty-two consecutive patients (70{\%} of all eligible patients) with drug-resistant TLE and IQ ≥ 70 completed the Minnesota Multiphasic Personality Inventory, the Beck Depression Inventory, the Spielberger State-Trait Anxiety Inventory, and the Spielberger State-Trait Anger Expression Inventory before surgical treatment, after one year, and after two years. During the follow-up period, patients were maintained on a stable medication regimen. Repeated measures analysis of variance was used to examine changes in psychiatric variables over time. Results: Seizure outcome was excellent (89{\%} in Engel class I after 2 years). After surgery, the only significant change in personality variables was a decrease in social introversion. Anxiety decreased significantly with a gradual decline, anger dropped significantly after remaining basically flat during the first year, while depression showed a gradual but non-significant decline. Younger age and shorter duration of epilepsy were associated with greater improvement in several anger dimensions. Conclusion: The profile of emotional distress and its relatively slow decrease over time suggest that patients may experience difficulties in switching from a 'sick' role to a 'normal' role and may easily be disappointed if expectations of positive life changes are not rapidly met. Some counselling sessions early after surgery may be useful to address these issues. Surgery may yield greater emotional benefits if performed early.",
keywords = "Anger, Anxiety, Depression, Personality, Temporal lobe epilepsy",
author = "Grammaldo, {L. G.} and A. Picardi and T. Giamp{\`a} and {De Risi}, M. and Quarato, {P. P.} and {Di Bonaventura}, C. and V. Esposito and {Di Gennaro}, G.",
year = "2008",
month = "5",
language = "Italian",
pages = "207--209",
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T1 - Studio osservazionale delle modificazioni della rabbia, depressione, ansia e personalità dopo lobectomia temporale effettuata per epilessia parziale farmacoresistente

AU - Grammaldo, L. G.

AU - Picardi, A.

AU - Giampà, T.

AU - De Risi, M.

AU - Quarato, P. P.

AU - Di Bonaventura, C.

AU - Esposito, V.

AU - Di Gennaro, G.

PY - 2008/5

Y1 - 2008/5

N2 - Objective: To further elucidate the psychiatric outcome of surgical treatment for temporal lobe epilepsy (TLE). Methods: Fifty-two consecutive patients (70% of all eligible patients) with drug-resistant TLE and IQ ≥ 70 completed the Minnesota Multiphasic Personality Inventory, the Beck Depression Inventory, the Spielberger State-Trait Anxiety Inventory, and the Spielberger State-Trait Anger Expression Inventory before surgical treatment, after one year, and after two years. During the follow-up period, patients were maintained on a stable medication regimen. Repeated measures analysis of variance was used to examine changes in psychiatric variables over time. Results: Seizure outcome was excellent (89% in Engel class I after 2 years). After surgery, the only significant change in personality variables was a decrease in social introversion. Anxiety decreased significantly with a gradual decline, anger dropped significantly after remaining basically flat during the first year, while depression showed a gradual but non-significant decline. Younger age and shorter duration of epilepsy were associated with greater improvement in several anger dimensions. Conclusion: The profile of emotional distress and its relatively slow decrease over time suggest that patients may experience difficulties in switching from a 'sick' role to a 'normal' role and may easily be disappointed if expectations of positive life changes are not rapidly met. Some counselling sessions early after surgery may be useful to address these issues. Surgery may yield greater emotional benefits if performed early.

AB - Objective: To further elucidate the psychiatric outcome of surgical treatment for temporal lobe epilepsy (TLE). Methods: Fifty-two consecutive patients (70% of all eligible patients) with drug-resistant TLE and IQ ≥ 70 completed the Minnesota Multiphasic Personality Inventory, the Beck Depression Inventory, the Spielberger State-Trait Anxiety Inventory, and the Spielberger State-Trait Anger Expression Inventory before surgical treatment, after one year, and after two years. During the follow-up period, patients were maintained on a stable medication regimen. Repeated measures analysis of variance was used to examine changes in psychiatric variables over time. Results: Seizure outcome was excellent (89% in Engel class I after 2 years). After surgery, the only significant change in personality variables was a decrease in social introversion. Anxiety decreased significantly with a gradual decline, anger dropped significantly after remaining basically flat during the first year, while depression showed a gradual but non-significant decline. Younger age and shorter duration of epilepsy were associated with greater improvement in several anger dimensions. Conclusion: The profile of emotional distress and its relatively slow decrease over time suggest that patients may experience difficulties in switching from a 'sick' role to a 'normal' role and may easily be disappointed if expectations of positive life changes are not rapidly met. Some counselling sessions early after surgery may be useful to address these issues. Surgery may yield greater emotional benefits if performed early.

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KW - Anxiety

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