Abstract
In marathon runners changes in red blood cell count, haematocrit and haemoglobin in relation to haemodilution have been reported. Moreover, it has been hypothesized that strenous exercise induces oxidant stress through several different mechanisms. This study investigated the haematological variables, iron status and oxidative indices before, immediately and 48 h after a race in 8 healthy trained males aged 33-44 years running a 21-km marathon in 79±3 min. The haematological parameters were determined by standard procedures. Erythropoietin and soluble-transferrin receptor were evaluated immunoenzymatically. Nontransferrin-bound iron (NTBI) was assayed by high-performance liquid chromatography after nitrilotriacetic acid chelation. Malonyldialdehyde (MDA) concentration was assayed colorimetrically. The total number of reticulocytes rose significantly after the run with a significant increase in the high-RNA-content fraction (14±5, p
| Original language | English |
|---|---|
| Pages (from-to) | 30-34 |
| Number of pages | 5 |
| Journal | Internal and Emergency Medicine |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Apr 2006 |
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Keywords
- Exercise
- Malonyldialdehyde
- Reticulocytes
- Transferrin receptors
ASJC Scopus subject areas
- Emergency Medicine
- Internal Medicine
Cite this
Changes in erythropoiesis, iron metabolism and oxidative stress after half-marathon. / Duca, Lorena; Da Ponte, Alessandro; Cozzi, Mariarita; Carbone, Annalisa; Pomati, Mauro; Nava, Isabella; Cappellini, Maria Domenica; Fiorelli, Gemino.
In: Internal and Emergency Medicine, Vol. 1, No. 1, 04.2006, p. 30-34.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Changes in erythropoiesis, iron metabolism and oxidative stress after half-marathon
AU - Duca, Lorena
AU - Da Ponte, Alessandro
AU - Cozzi, Mariarita
AU - Carbone, Annalisa
AU - Pomati, Mauro
AU - Nava, Isabella
AU - Cappellini, Maria Domenica
AU - Fiorelli, Gemino
PY - 2006/4
Y1 - 2006/4
N2 - In marathon runners changes in red blood cell count, haematocrit and haemoglobin in relation to haemodilution have been reported. Moreover, it has been hypothesized that strenous exercise induces oxidant stress through several different mechanisms. This study investigated the haematological variables, iron status and oxidative indices before, immediately and 48 h after a race in 8 healthy trained males aged 33-44 years running a 21-km marathon in 79±3 min. The haematological parameters were determined by standard procedures. Erythropoietin and soluble-transferrin receptor were evaluated immunoenzymatically. Nontransferrin-bound iron (NTBI) was assayed by high-performance liquid chromatography after nitrilotriacetic acid chelation. Malonyldialdehyde (MDA) concentration was assayed colorimetrically. The total number of reticulocytes rose significantly after the run with a significant increase in the high-RNA-content fraction (14±5, p
AB - In marathon runners changes in red blood cell count, haematocrit and haemoglobin in relation to haemodilution have been reported. Moreover, it has been hypothesized that strenous exercise induces oxidant stress through several different mechanisms. This study investigated the haematological variables, iron status and oxidative indices before, immediately and 48 h after a race in 8 healthy trained males aged 33-44 years running a 21-km marathon in 79±3 min. The haematological parameters were determined by standard procedures. Erythropoietin and soluble-transferrin receptor were evaluated immunoenzymatically. Nontransferrin-bound iron (NTBI) was assayed by high-performance liquid chromatography after nitrilotriacetic acid chelation. Malonyldialdehyde (MDA) concentration was assayed colorimetrically. The total number of reticulocytes rose significantly after the run with a significant increase in the high-RNA-content fraction (14±5, p
KW - Exercise
KW - Malonyldialdehyde
KW - Reticulocytes
KW - Transferrin receptors
UR - http://www.scopus.com/inward/record.url?scp=33750120519&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750120519&partnerID=8YFLogxK
U2 - 10.1007/BF02934717
DO - 10.1007/BF02934717
M3 - Article
C2 - 16941810
AN - SCOPUS:33750120519
VL - 1
SP - 30
EP - 34
JO - Internal and Emergency Medicine
JF - Internal and Emergency Medicine
SN - 1828-0447
IS - 1
ER -