Changes in movement-related brain activity during transient deafferentation: A neuromagnetic study

Rumyana Kristeva-Feige, Simone Rossi, Vittorio Pizzella, Alessandro Sabato, Franca Tecchio, Bernd Feige, Gian Luca Romani, Jochen Edrich, Paolo Maria Rossini

Research output: Contribution to journalArticle

Abstract

Neuromagnetic fields from the left cerebral hemisphere of three healthy, right-handed subjects were investigated preceding and during voluntary index finger movements performed every 8-15 s under two different experimental conditions: before (stage A) and during (stage B) anesthetic block of median and radial nerves at the wrist. The anesthesia caused blocking of cutaneous receptors and some of the proprioreceptors from a wide hand area, including the entire index finger. However, the index finger movements were not impaired because the muscles participating in the task were not anesthetized. The magnetic signals of the brain sources corresponding to the main components of the movement-related neuromagnetic fields (motor field, MF and movement-evoked field I, MEFI) were mapped and localized using a moving dipole model. In the three investigated subjects the MF and MEFI dipole sources were stronger (30% on average) during stage B than during stage A. No significant changes in spatial coordinates of the estimated dipole locations between stages A and B were observed. This was true for both MF and MEFI. The results show that the MEFI reflects not only proprioceptive input from the periphery but cutaneous inputs as well. In this way the results support the view that cutaneous inputs play a specific role in the cortical control of movement.

Original languageEnglish
Pages (from-to)201-208
Number of pages8
JournalBrain Research
Volume714
Issue number1-2
DOIs
Publication statusPublished - Apr 1 1996

Fingerprint

Fingers
Skin
Brain
Radial Nerve
Median Nerve
Cerebrum
Wrist
Anesthetics
Anesthesia
Hand
Muscles

Keywords

  • Anesthesia
  • Human
  • Magnetoencephalography
  • Motor field
  • Movement-evoked field I
  • Movement-related magnetic field
  • Somatosensory cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Changes in movement-related brain activity during transient deafferentation : A neuromagnetic study. / Kristeva-Feige, Rumyana; Rossi, Simone; Pizzella, Vittorio; Sabato, Alessandro; Tecchio, Franca; Feige, Bernd; Romani, Gian Luca; Edrich, Jochen; Rossini, Paolo Maria.

In: Brain Research, Vol. 714, No. 1-2, 01.04.1996, p. 201-208.

Research output: Contribution to journalArticle

Kristeva-Feige, R, Rossi, S, Pizzella, V, Sabato, A, Tecchio, F, Feige, B, Romani, GL, Edrich, J & Rossini, PM 1996, 'Changes in movement-related brain activity during transient deafferentation: A neuromagnetic study', Brain Research, vol. 714, no. 1-2, pp. 201-208. https://doi.org/10.1016/0006-8993(95)01537-X
Kristeva-Feige R, Rossi S, Pizzella V, Sabato A, Tecchio F, Feige B et al. Changes in movement-related brain activity during transient deafferentation: A neuromagnetic study. Brain Research. 1996 Apr 1;714(1-2):201-208. https://doi.org/10.1016/0006-8993(95)01537-X
Kristeva-Feige, Rumyana ; Rossi, Simone ; Pizzella, Vittorio ; Sabato, Alessandro ; Tecchio, Franca ; Feige, Bernd ; Romani, Gian Luca ; Edrich, Jochen ; Rossini, Paolo Maria. / Changes in movement-related brain activity during transient deafferentation : A neuromagnetic study. In: Brain Research. 1996 ; Vol. 714, No. 1-2. pp. 201-208.
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