MODIFICAZIONI DEL SONNO NOTTURNO E DELLA SONNOLENZA DIURNA DOPO SOMMINISTRAZIONE DI CARBAMAZEPINA

Translated title of the contribution: Changes in nocturnal sleep and day time somnolence after CBZ administration

G. L. Gigli, M. Diomedi, F. Placidi, M. C E Maschio, F. Baldinetti, F. Pauri, L. Ciocari, M. E. Marciani

Research output: Contribution to journalArticle

Abstract

Despite a large clinical use, very little is known about sleep changes caused by carbamazepine (CBZ) administration in epileptic patients. Night sleep organisation and daytime somnolence have been studied in 7 temporal lobe epileptic patients and in 6 healthy controls in basal condition and after 400 mg of CBZ. Only patients have also been recorded after one month daily treatment with CBZ-CR 800 mg. In basal condition the epileptic patients do not differ from the control group. After the first CBZ administration, both groups present a reduction and fragmentation of REM sleep, and an increased daytime somnolence. After chronic use, sleep alteration tend to return to baseline. Finally, CBZ does not cause alterations of sleep microstructure.

Translated title of the contributionChanges in nocturnal sleep and day time somnolence after CBZ administration
Original languageItalian
Pages (from-to)375-376
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number86-87
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Gigli, G. L., Diomedi, M., Placidi, F., Maschio, M. C. E., Baldinetti, F., Pauri, F., Ciocari, L., & Marciani, M. E. (1994). MODIFICAZIONI DEL SONNO NOTTURNO E DELLA SONNOLENZA DIURNA DOPO SOMMINISTRAZIONE DI CARBAMAZEPINA. Bollettino - Lega Italiana contro l'Epilessia, (86-87), 375-376.