Changes in PgR and Ki-67 in residual tumour and outcome of breast cancer patients treated with neoadjuvant chemotherapy

Emilia Montagna, V. Bagnardi, G. Viale, N. Rotmensz, A. Sporchia, G. Cancello, A. Balduzzi, V. Galimberti, P. Veronesi, A. Luini, M. G. Mastropasqua, C. Casadio, C. Sangalli, A. Goldhirsch, M. Colleoni

Research output: Contribution to journalArticlepeer-review

Abstract

We collected information on 904 consecutive breast cancer patients treated with neoadjuvant chemotherapy at the European Institute of Oncology, Milan, Italy, between 1999 and 2011. The decrease of PgR and Ki-67 expression after preoperative chemotherapy has a prognostic role in breast cancer patients with residual disease.

Original languageEnglish
Article numbermdu528
Pages (from-to)307-313
Number of pages7
JournalAnnals of Oncology
Volume26
Issue number2
DOIs
Publication statusPublished - Feb 1 2015

Keywords

  • Breast cancer
  • Chemotherapy
  • HER2
  • Hormonal receptors
  • Neoadjuvant therapy
  • Surgery

ASJC Scopus subject areas

  • Oncology
  • Hematology

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