Changes in surface electrocardiogram in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary endarterectomy. Correlations with hemodynamic and echocardiographic improvements after surgery

Stefano Ghio, Annalisa Turco, Catherine Klersy, Laura Scelsi, Claudia Raineri, Valeria Crescio, Arianna Viscardi, Valentina Grazioli, Antonio Sciortino, Luigi Oltrona Visconti, Andrea Maria D'Armini

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4 Citations (Scopus)

Abstract

Background The aim of the present study was to evaluate the changes of electrocardiographic (ECG) markers of right ventricular (RV) hypertrophy/overload in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA). Methods and results We evaluated 99 CTEPH patients who underwent PEA. P wave amplitude in DII, R wave amplitude in V1 and the number of patients with negative T wave in V1-V3 decreased significantly at 1 month after surgery with no further change at 1 year, in parallel with the rapid improvement in right heart hemodynamics. S wave amplitude in V1, R:S wave ratio in lead V6 and prevalence of SIQIII pattern improved significantly at 1 year, in parallel with the progressive reverse remodeling of the right ventricle at echocardiography. Conclusions The study shows that some of the ECG markers of RV hypertrophy/overload better reflect RV hemodynamic overload while others better reflect the pathologic remodeling of the right ventricle.

Original languageEnglish
Pages (from-to)223-230
Number of pages8
JournalJournal of Electrocardiology
Volume49
Issue number2
DOIs
Publication statusPublished - Mar 1 2016

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Endarterectomy
Pulmonary Hypertension
Right Ventricular Hypertrophy
Electrocardiography
Hemodynamics
Lung
Heart Ventricles
Echocardiography

Keywords

  • Electrocardiogram
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Changes in surface electrocardiogram in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary endarterectomy. Correlations with hemodynamic and echocardiographic improvements after surgery",
abstract = "Background The aim of the present study was to evaluate the changes of electrocardiographic (ECG) markers of right ventricular (RV) hypertrophy/overload in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA). Methods and results We evaluated 99 CTEPH patients who underwent PEA. P wave amplitude in DII, R wave amplitude in V1 and the number of patients with negative T wave in V1-V3 decreased significantly at 1 month after surgery with no further change at 1 year, in parallel with the rapid improvement in right heart hemodynamics. S wave amplitude in V1, R:S wave ratio in lead V6 and prevalence of SIQIII pattern improved significantly at 1 year, in parallel with the progressive reverse remodeling of the right ventricle at echocardiography. Conclusions The study shows that some of the ECG markers of RV hypertrophy/overload better reflect RV hemodynamic overload while others better reflect the pathologic remodeling of the right ventricle.",
keywords = "Electrocardiogram, Pulmonary hypertension",
author = "Stefano Ghio and Annalisa Turco and Catherine Klersy and Laura Scelsi and Claudia Raineri and Valeria Crescio and Arianna Viscardi and Valentina Grazioli and Antonio Sciortino and {Oltrona Visconti}, Luigi and D'Armini, {Andrea Maria}",
year = "2016",
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day = "1",
doi = "10.1016/j.jelectrocard.2015.12.006",
language = "English",
volume = "49",
pages = "223--230",
journal = "Journal of Electrocardiology",
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TY - JOUR

T1 - Changes in surface electrocardiogram in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary endarterectomy. Correlations with hemodynamic and echocardiographic improvements after surgery

AU - Ghio, Stefano

AU - Turco, Annalisa

AU - Klersy, Catherine

AU - Scelsi, Laura

AU - Raineri, Claudia

AU - Crescio, Valeria

AU - Viscardi, Arianna

AU - Grazioli, Valentina

AU - Sciortino, Antonio

AU - Oltrona Visconti, Luigi

AU - D'Armini, Andrea Maria

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Background The aim of the present study was to evaluate the changes of electrocardiographic (ECG) markers of right ventricular (RV) hypertrophy/overload in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA). Methods and results We evaluated 99 CTEPH patients who underwent PEA. P wave amplitude in DII, R wave amplitude in V1 and the number of patients with negative T wave in V1-V3 decreased significantly at 1 month after surgery with no further change at 1 year, in parallel with the rapid improvement in right heart hemodynamics. S wave amplitude in V1, R:S wave ratio in lead V6 and prevalence of SIQIII pattern improved significantly at 1 year, in parallel with the progressive reverse remodeling of the right ventricle at echocardiography. Conclusions The study shows that some of the ECG markers of RV hypertrophy/overload better reflect RV hemodynamic overload while others better reflect the pathologic remodeling of the right ventricle.

AB - Background The aim of the present study was to evaluate the changes of electrocardiographic (ECG) markers of right ventricular (RV) hypertrophy/overload in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing pulmonary endarterectomy (PEA). Methods and results We evaluated 99 CTEPH patients who underwent PEA. P wave amplitude in DII, R wave amplitude in V1 and the number of patients with negative T wave in V1-V3 decreased significantly at 1 month after surgery with no further change at 1 year, in parallel with the rapid improvement in right heart hemodynamics. S wave amplitude in V1, R:S wave ratio in lead V6 and prevalence of SIQIII pattern improved significantly at 1 year, in parallel with the progressive reverse remodeling of the right ventricle at echocardiography. Conclusions The study shows that some of the ECG markers of RV hypertrophy/overload better reflect RV hemodynamic overload while others better reflect the pathologic remodeling of the right ventricle.

KW - Electrocardiogram

KW - Pulmonary hypertension

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