In 9 Sardinian females heterozygous for glucose 6 phosphate dehydrogenase (G 6PD) deficiency the 2 red cell populations, during and after hemolytic crises, were studied. The quantitative variation of G 6PD in individual erythrocytes was performed by spectrophotometric assay and by a cytochemical estimation based on differential scoring. Blood samples were taken on admission during hemolytic crisis and on the 5th day; control tests were carried out 4 mth after the crisis. Differential scoring demonstrated an increase of cells with a normal content of G 6PD on the 5th day after the hemolytic crisis coinciding with the peak in reticulocyte count.
|Translated title of the contribution||Changes in the ratio between normal and sensitive red cells in Sardinian women heterozygous for G 6PD deficiency (Gd(b)/Gd(med)) during hemolytic crises|
|Title of host publication||QUAD.SCLAVO DIAGN.CLIN.LAB.|
|Number of pages||8|
|Publication status||Published - 1973|
ASJC Scopus subject areas