Changes in the water holding capacity of psoriatic stratum corneum in vivo

G. Borroni, G. Vignati, V. Brazzelli, G. P. Vignoli, P. Gabba, M. Gatti, E. Berardesca, A. Cosseta, G. Rabbiosi

Research output: Contribution to journalArticlepeer-review

Abstract

This study investigated the functional capacity of the stratum corneum of psoriatic skin to bind water in vivo during a relatively long period of time (water holding capacity - WHC). An electrical capacitance test was applied to the psoriatic skin on the elbows, perilesional skin and apparently normal skin of 11 patients and the elbows of 10 controls. Measurements of electrical capacitance were performed using a Corneometer Schwarzhaupt for 25 min. The WHC levels were calculated for this period. Our results demonstrate that the WHC of psoriatic stratum corneum does not differ from controls in the first 10 min. Only after the 20th min do the WHCs differ significantly (p <0.02). Despite the biochemical keratin changes in sporiatic plaque, the latter is highly hygroscopic, in particular in the first minute after bathing. Perilesional skin binds water like the stratum corneum of controls, though not beyond the 20th minute after bathing.

Original languageEnglish
Pages (from-to)192-194
Number of pages3
JournalActa Dermato-Venereologica, Supplement
Volume69
Issue number146
Publication statusPublished - 1989

Keywords

  • Hygroscopicity
  • Psoriasis
  • Water holding capacity

ASJC Scopus subject areas

  • Dermatology

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