Changes of autonomic cardiac profile after a 3-week integrated body weight reduction program in severely obese patients

M. Facchini, G. Malfatto, L. Sala, G. Silvestri, P. Fontana, C. Lafortuna, Alessandro Sartorio

Research output: Contribution to journalArticlepeer-review

Abstract

The autonomic control of the heart is abnormal in obese subjects due to a prevalence of sympathetic over parasympathetic limb of the autonomic balance. We evaluated the effects of a short-term (3 weeks) integrated body weight reduction program (consisting of energy restricted diet and high-intensity exercise training) on heart rate variability (HRV) in severely obese, normotensive patients. The HRV was evaluated both in the time and frequency domain over a 18-hour Holter recording period obtained before and at the end of the third week. Three-week body weight reduction program reduced BMI (from 41.4±4.6 to 39.5±4.3 kg/m2, -4.6%, p

Original languageEnglish
Pages (from-to)138-142
Number of pages5
JournalJournal of Endocrinological Investigation
Volume26
Issue number2
Publication statusPublished - Feb 2003

Keywords

  • Autonomic nervous system
  • Cardiovascular risk
  • Obesity
  • Physical training
  • Weight reduction

ASJC Scopus subject areas

  • Endocrinology

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