Changes of motor cortical excitability in human subjects from wakefulness to early stages of sleep: A combined transcranial magnetic stimulation and electroencephalographic study

Paolo Manganotti, Giorgio Fuggetta, Antonio Fiaschi

Research output: Contribution to journalArticle

Abstract

The effect of sleep on human motor cortical excitability was investigated by evaluating the latency and amplitude of motor evoked potentials in ten subjects using transcranial magnetic stimulation. Motor evoked potentials and electroencephalographic data were recorded simultaneously and analyzed. Recordings were performed before, during and after a sleep period. A significant decrease in motor evoked potentials amplitude and a slight change in motor evoked potentials latency were noted in the recordings during the different sleep stages with a return to baseline values on awakening. A decrease in motor cortical excitability is suggested as explaining the effect of sleep.

Original languageEnglish
Pages (from-to)31-34
Number of pages4
JournalNeuroscience Letters
Volume362
Issue number1
DOIs
Publication statusPublished - May 13 2004

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Motor Evoked Potentials
Transcranial Magnetic Stimulation
Wakefulness
Sleep Stages
Sleep
Cortical Excitability

Keywords

  • Cortical inhibition
  • Epilepsy
  • Sleep
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Changes of motor cortical excitability in human subjects from wakefulness to early stages of sleep : A combined transcranial magnetic stimulation and electroencephalographic study. / Manganotti, Paolo; Fuggetta, Giorgio; Fiaschi, Antonio.

In: Neuroscience Letters, Vol. 362, No. 1, 13.05.2004, p. 31-34.

Research output: Contribution to journalArticle

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