Changing pattern of pathogens causing broviac catheter-related bacteraemias in children with cancer

E. Castagnola, A. Garaventa, C. Viscoli, G. Carrega, M. Nantron, C. Molinari, C. Moroni, R. Giacchino

Research output: Contribution to journalArticlepeer-review


The incidence of pathogens causing catheter-related bacteraemias in children undergoing antineoplastic chemotherapy with or without bone marrow transplantation at G. Gaslini Children's Hospital, Genoa, Italy, was analysed by comparing data from a retrospective study (1985-1988) with that obtained from a prospective one (1989-1992). In both periods catheter-related bacteraemias one (1989-1992). In both periods cathete-rrelated bacteraemias were more frequent in non-neutropenic than in neutropenic patients. Among catheter-unrelated bacteraemias the pattern of infecting pathogens remained unchanged between the study periods, with Gram-positive bacteria remaining the predominant pathogens. Conversely, among catheter-related bacteraemias, the incidence of Gram-negative bacilli increased significantly from 3 to 38%, and that of Gram-positive bacteria fell from 63 to 32% (P = 0·001, X2 test for heterogeneity).

Original languageEnglish
Pages (from-to)129-133
Number of pages5
JournalJournal of Hospital Infection
Issue number2
Publication statusPublished - 1995


  • antineoplastic chemotherapy
  • Bacteraemia
  • catheters

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Applied Microbiology and Biotechnology
  • Microbiology
  • Parasitology
  • Virology
  • Immunology and Allergy


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