Changing patterns of breast cancer stage at diagnosis in Southern Italy: Hospital data as indicators of progressive changes

Maurizio Montella, Marina Buonanno, Edoardo Biondi, Anna Crispo, Mariarosaria De Marco, Mario Tamburini, Gerardo Botti, Gabriella Fabbrocini, Immacolata Capasso, Giuseppe D'Aiuto

Research output: Contribution to journalArticle

Abstract

Background. In southern Italy diagnostic delay in breast cancer patients has been demonstrated to be related to the level of education and residency in rural areas. In order to verify whether late breast cancer diagnosis was actually in decline as a result of improving socioeconomic conditions and ongoing prevention programs, we evaluated clinical data from the tumor registry of the National Cancer Institute, Naples. Methods. Four thousand two hundred forty consecutive breast cancer patients admitted to our institution from 1986 to 1997 were grouped into four 3-year periods according to their admission date. Using multiple logistic regression, χ2 for trend and β- coefficient were calculated in each pT and pN categories in order to discover the trend for the 1986-1997 period. Results. A progressive, statistically significant decrease in the number of patients with advanced cancer at the time of diagnosis was observed over the study period. In particular, χ2 values for trend for each pT category, over the study period, were pT1 119.4 (P <0.001) with positive β-coefficient, pT2 13.4 (P = 0.003) with negative β, and pT3-pT4 152.2 (P <0.001) with the strongest negative β. Conclusions. Changing patterns of breast cancer stage at diagnosis have been demonstrated in women living in Southern Italy. They are consistent with an increasing orientation toward prevention. Data from hospital tumor registries are a useful source of information on diagnostic delay. (C) 2000 American Health Foundation and Academic Press.

Original languageEnglish
Pages (from-to)174-177
Number of pages4
JournalPreventive Medicine
Volume30
Issue number2
DOIs
Publication statusPublished - Feb 2000

Fingerprint

Italy
Breast Neoplasms
Registries
Neoplasms
National Cancer Institute (U.S.)
Internship and Residency
Logistic Models
Education

Keywords

  • Breast cancer
  • Diagnostic delay
  • Prevention
  • Staging
  • Tumor registry

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Changing patterns of breast cancer stage at diagnosis in Southern Italy : Hospital data as indicators of progressive changes. / Montella, Maurizio; Buonanno, Marina; Biondi, Edoardo; Crispo, Anna; De Marco, Mariarosaria; Tamburini, Mario; Botti, Gerardo; Fabbrocini, Gabriella; Capasso, Immacolata; D'Aiuto, Giuseppe.

In: Preventive Medicine, Vol. 30, No. 2, 02.2000, p. 174-177.

Research output: Contribution to journalArticle

Montella, M, Buonanno, M, Biondi, E, Crispo, A, De Marco, M, Tamburini, M, Botti, G, Fabbrocini, G, Capasso, I & D'Aiuto, G 2000, 'Changing patterns of breast cancer stage at diagnosis in Southern Italy: Hospital data as indicators of progressive changes', Preventive Medicine, vol. 30, no. 2, pp. 174-177. https://doi.org/10.1006/pmed.1999.0595
Montella, Maurizio ; Buonanno, Marina ; Biondi, Edoardo ; Crispo, Anna ; De Marco, Mariarosaria ; Tamburini, Mario ; Botti, Gerardo ; Fabbrocini, Gabriella ; Capasso, Immacolata ; D'Aiuto, Giuseppe. / Changing patterns of breast cancer stage at diagnosis in Southern Italy : Hospital data as indicators of progressive changes. In: Preventive Medicine. 2000 ; Vol. 30, No. 2. pp. 174-177.
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