Changing spectrum and outcome of 705 fet al congenital heart disease cases: 12 years, experience in a third-level center

Maria G. Russo, Dario Paladini, Giuseppe Pacileo, Concetta Ricci, Giovanni Di Salvo, Maria Felicetti, Laura Di Pietto, Antonio Tartaglione, Maria T. Palladino, Giuseppe Santoro, Giuseppe Caianiello, Carlo Vosa, Raffaele Calabro

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction Congenital heart diseases are the most common prenatal and postnatal malformations. Nowadays, fet al echocardiography is a widely practiced technique; however, the impact of prenatal diagnosis on prognosis of the newborns affected by congenital heart disease remains uncertain. Objective To assess the outcome and the changes in the spectrum of prenatally detected congenital heart disease in our tertiary care centre in 12 years of activity (1995-2006). Methods and results We detected 705 congenital heart diseases: 32% (223) were associated with extracardiac or chromosomal anomalies or both, and 68% (482) were isolated. Termination of pregnancy was chosen in 81% for associated anomalies and 37% for isolated anomalies (P

Original languageEnglish
Pages (from-to)910-915
Number of pages6
JournalJournal of Cardiovascular Medicine
Volume9
Issue number9
Publication statusPublished - Sep 2008

Keywords

  • Congenital heart disease
  • Effectiveness of prenatal diagnosis
  • Fet al echocardiography
  • Heart disease
  • Outcome of prenatally detected congenital
  • Trends in prenatal diagnosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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