TY - JOUR
T1 - Chapter 16. Membrane and soluble pattern recognition receptors
T2 - The unique functions of the long pentraxin PTX3
AU - Mantovani, Alberto
AU - Garlanda, C.
AU - Otero, K.
AU - Peri, G.
AU - Vecchi, A.
AU - Bottazzi, B.
PY - 2004/12
Y1 - 2004/12
N2 - Pentraxin 3 (PTX3), the first long pentraxin identified, is characterized by a C-terminal pentraxin like domain, showing sequence similarity to C-reactive protein and serum amyloid P component, coupled with a N-terminal unrelated portion. PTX3 is made by diverse cell types, including endothelial cells, macrophages and dendritic cells, in response to proinflammatory signals such as interleukin 1, tumor necrosis factor and lipopolysaccharide. It binds different ligands, including Clq, apoptotic cells and microbial mojcties. PTX3 levels are
AB - Pentraxin 3 (PTX3), the first long pentraxin identified, is characterized by a C-terminal pentraxin like domain, showing sequence similarity to C-reactive protein and serum amyloid P component, coupled with a N-terminal unrelated portion. PTX3 is made by diverse cell types, including endothelial cells, macrophages and dendritic cells, in response to proinflammatory signals such as interleukin 1, tumor necrosis factor and lipopolysaccharide. It binds different ligands, including Clq, apoptotic cells and microbial mojcties. PTX3 levels are
KW - Autoimmune disorders
KW - Fertility
KW - Inflammation
KW - Innate immunity
KW - Pattern recognition receptors
KW - Pentraxins
UR - http://www.scopus.com/inward/record.url?scp=11844275311&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=11844275311&partnerID=8YFLogxK
U2 - 10.1111/j.1472-9725.2004.00048.x
DO - 10.1111/j.1472-9725.2004.00048.x
M3 - Article
AN - SCOPUS:11844275311
VL - 4
SP - 150
EP - 154
JO - Clinical and Experimental Allergy Reviews
JF - Clinical and Experimental Allergy Reviews
SN - 1472-9725
IS - SUPPL. 2
ER -