Abstract
Treatment of hypertension in the elderly has become not only accepted but also a highly ethical, effective and compelling procedure following the many clearly positive reports on the benefits of lowering elevated arterial pressure in elderly patients. So far most intervention studies in elderly hypertensive patients have used diuretics or β-blockers or the two in combination as the moiety by which blood pressure has been lowered. However, from a theoretical point of view, more novel therapies could offer advantages that would translate into an even better reduction of cardiovascular morbidity and mortality than has been obtained with the traditional antihypertensive therapies used so far. Some of the studies in elderly hypertensives that are in progress using angiotensin converting enzyme inhibitors or calcium antagonists as the main therapies, e.g. the STOP-Hypertension-2 Study and the Syst-Eur Study, will be briefly reviewed here as will the large data base on urapidil, a dual action antihypertensive drug used in the treatment of elderly hypertensives. By careful evaluation of the effects of novel antihypertensive drugs, and the already existing data base on urapidil in elderly hypertensive patients, it is likely that still better reduction of risk can be obtained in the elderly hypertensives by the use of more novel therapies than diuretics and β-blockers.
| Original language | English |
|---|---|
| Pages (from-to) | 68-72 |
| Number of pages | 5 |
| Journal | Blood Pressure, Supplement |
| Volume | 4 |
| Issue number | 3 |
| Publication status | Published - 1995 |
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Keywords
- β-blockers
- Antihypertensive treatment
- Diuretics
- Elderly
- Hypertension
- Intervention
- Urapidil
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Internal Medicine
Cite this
Characteristics of an ideal antihypertensive therapy for elderly hypertensives. / Hansson, L.; Zanchetti, A.
In: Blood Pressure, Supplement, Vol. 4, No. 3, 1995, p. 68-72.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characteristics of an ideal antihypertensive therapy for elderly hypertensives
AU - Hansson, L.
AU - Zanchetti, A.
PY - 1995
Y1 - 1995
N2 - Treatment of hypertension in the elderly has become not only accepted but also a highly ethical, effective and compelling procedure following the many clearly positive reports on the benefits of lowering elevated arterial pressure in elderly patients. So far most intervention studies in elderly hypertensive patients have used diuretics or β-blockers or the two in combination as the moiety by which blood pressure has been lowered. However, from a theoretical point of view, more novel therapies could offer advantages that would translate into an even better reduction of cardiovascular morbidity and mortality than has been obtained with the traditional antihypertensive therapies used so far. Some of the studies in elderly hypertensives that are in progress using angiotensin converting enzyme inhibitors or calcium antagonists as the main therapies, e.g. the STOP-Hypertension-2 Study and the Syst-Eur Study, will be briefly reviewed here as will the large data base on urapidil, a dual action antihypertensive drug used in the treatment of elderly hypertensives. By careful evaluation of the effects of novel antihypertensive drugs, and the already existing data base on urapidil in elderly hypertensive patients, it is likely that still better reduction of risk can be obtained in the elderly hypertensives by the use of more novel therapies than diuretics and β-blockers.
AB - Treatment of hypertension in the elderly has become not only accepted but also a highly ethical, effective and compelling procedure following the many clearly positive reports on the benefits of lowering elevated arterial pressure in elderly patients. So far most intervention studies in elderly hypertensive patients have used diuretics or β-blockers or the two in combination as the moiety by which blood pressure has been lowered. However, from a theoretical point of view, more novel therapies could offer advantages that would translate into an even better reduction of cardiovascular morbidity and mortality than has been obtained with the traditional antihypertensive therapies used so far. Some of the studies in elderly hypertensives that are in progress using angiotensin converting enzyme inhibitors or calcium antagonists as the main therapies, e.g. the STOP-Hypertension-2 Study and the Syst-Eur Study, will be briefly reviewed here as will the large data base on urapidil, a dual action antihypertensive drug used in the treatment of elderly hypertensives. By careful evaluation of the effects of novel antihypertensive drugs, and the already existing data base on urapidil in elderly hypertensive patients, it is likely that still better reduction of risk can be obtained in the elderly hypertensives by the use of more novel therapies than diuretics and β-blockers.
KW - β-blockers
KW - Antihypertensive treatment
KW - Diuretics
KW - Elderly
KW - Hypertension
KW - Intervention
KW - Urapidil
UR - http://www.scopus.com/inward/record.url?scp=0028866807&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028866807&partnerID=8YFLogxK
M3 - Article
C2 - 8535546
AN - SCOPUS:0028866807
VL - 4
SP - 68
EP - 72
JO - Blood Pressure, Supplement
JF - Blood Pressure, Supplement
SN - 0803-8023
IS - 3
ER -