Characteristics of anxiety and psychological well-being in chronic post-stroke patients

Guido Edoardo D'Aniello, Federica Scarpina, Alessandro Mauro, Ileana Mori, Gianluca Castelnuovo, Matteo Bigoni, Silvia Baudo, Enrico Molinari

Research output: Contribution to journalArticlepeer-review


Background and purpose Anxiety and depression are common psychological conditions in post-stroke patients. In the present study, their relation with perceived quality of life and psychophysical well-being was investigated. Methods In the present cross-sectional study, chronic post-stroke patients (n = 81; average years from stroke = 4 ± 4.6) were assessed with the Hospital Anxiety and Depression Scale (HADS), the 36-item Short-Form Healthy Survey (SF-36) and the Psychological General Well-Being Index (PGWBI), as well as a brief neuropsychological assessment focused on the thinking ability and executive functions. Results Higher levels of anxiety compared to depressive symptoms were found. Hierarchical multiple regressions indicated that SF-36 predicts neither anxiety nor depression, and PGWBI subscales only partially. Conclusion Post-stroke anxiety can be a largely observed psychological distress in chronic patients: this pattern would be interpreted in relation to patients' expectations about their health status during a rehabilitation follow-up. SF-36 and PGWBI questionnaires did not provide satisfactory and reliable indexes: the relation between anxiety and both quality of life and psychological well-being needs further exploration.

Original languageEnglish
Pages (from-to)191-196
Number of pages6
JournalJournal of the Neurological Sciences
Issue number1-2
Publication statusPublished - Mar 15 2014


  • Anxiety
  • Cognition
  • Depression
  • Quality of life
  • Stroke
  • Well-being

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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