Abstract
Aim of this study was to determine whether menstrual attacks differ from non-menstrual attacks (NMA) as regards clinical features or response to abortive treatment in women affected by menstrually related migraine (MRM) referred to tertiary care centres. Sixty-four women with MRM were enrolled in a 2-month diary study Perimenstrual attacks were split into three groups - premenstrual (PMA), menstrual (MA) and late menstrual (LMA) - and compared to nonmenstrual ones. Perimenstrual attacks were significantly longer than NMA. No other migraine attack features were found to differ between the various phases of the cycle. Migraine work-related disability was significantly greater in PMA and MA than in NMA. Acute attack treatment was less effective in perimenstrual attacks. Pain-free at 2 h after dosage was achieved in 13.5% of MA (OR 0.41; 95% CI 0.22, 0.76) vs. 32.9% of NMA. We concluded that, in MRM, perimenstrual attacks are longer and less responsive to acute attack treatment than NMA.
| Original language | English |
|---|---|
| Pages (from-to) | 707-716 |
| Number of pages | 10 |
| Journal | Cephalalgia |
| Volume | 24 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 2004 |
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Keywords
- Acute attack treatment
- Menstrual cycle
- Menstrually related migraine
- Migraine without aura
ASJC Scopus subject areas
- Clinical Neurology
Cite this
Characteristics of menstrual and nonmenstrual attacks in women with menstrually related migraine referred to headache centres. / Granella, F.; Sances, G.; Allais, G.; Nappi, R. E.; Tirelli, A.; Benedetto, C.; Brundu, B.; Facchinetti, F.; Nappi, G.
In: Cephalalgia, Vol. 24, No. 9, 09.2004, p. 707-716.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characteristics of menstrual and nonmenstrual attacks in women with menstrually related migraine referred to headache centres
AU - Granella, F.
AU - Sances, G.
AU - Allais, G.
AU - Nappi, R. E.
AU - Tirelli, A.
AU - Benedetto, C.
AU - Brundu, B.
AU - Facchinetti, F.
AU - Nappi, G.
PY - 2004/9
Y1 - 2004/9
N2 - Aim of this study was to determine whether menstrual attacks differ from non-menstrual attacks (NMA) as regards clinical features or response to abortive treatment in women affected by menstrually related migraine (MRM) referred to tertiary care centres. Sixty-four women with MRM were enrolled in a 2-month diary study Perimenstrual attacks were split into three groups - premenstrual (PMA), menstrual (MA) and late menstrual (LMA) - and compared to nonmenstrual ones. Perimenstrual attacks were significantly longer than NMA. No other migraine attack features were found to differ between the various phases of the cycle. Migraine work-related disability was significantly greater in PMA and MA than in NMA. Acute attack treatment was less effective in perimenstrual attacks. Pain-free at 2 h after dosage was achieved in 13.5% of MA (OR 0.41; 95% CI 0.22, 0.76) vs. 32.9% of NMA. We concluded that, in MRM, perimenstrual attacks are longer and less responsive to acute attack treatment than NMA.
AB - Aim of this study was to determine whether menstrual attacks differ from non-menstrual attacks (NMA) as regards clinical features or response to abortive treatment in women affected by menstrually related migraine (MRM) referred to tertiary care centres. Sixty-four women with MRM were enrolled in a 2-month diary study Perimenstrual attacks were split into three groups - premenstrual (PMA), menstrual (MA) and late menstrual (LMA) - and compared to nonmenstrual ones. Perimenstrual attacks were significantly longer than NMA. No other migraine attack features were found to differ between the various phases of the cycle. Migraine work-related disability was significantly greater in PMA and MA than in NMA. Acute attack treatment was less effective in perimenstrual attacks. Pain-free at 2 h after dosage was achieved in 13.5% of MA (OR 0.41; 95% CI 0.22, 0.76) vs. 32.9% of NMA. We concluded that, in MRM, perimenstrual attacks are longer and less responsive to acute attack treatment than NMA.
KW - Acute attack treatment
KW - Menstrual cycle
KW - Menstrually related migraine
KW - Migraine without aura
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UR - http://www.scopus.com/inward/citedby.url?scp=4444356861&partnerID=8YFLogxK
U2 - 10.1111/j.1468-2982.2004.00741.x
DO - 10.1111/j.1468-2982.2004.00741.x
M3 - Article
C2 - 15315526
AN - SCOPUS:4444356861
VL - 24
SP - 707
EP - 716
JO - Cephalalgia
JF - Cephalalgia
SN - 0333-1024
IS - 9
ER -