TY - JOUR
T1 - Characteristics of menstrual and nonmenstrual attacks in women with menstrually related migraine referred to headache centres
AU - Granella, F.
AU - Sances, G.
AU - Allais, G.
AU - Nappi, R. E.
AU - Tirelli, A.
AU - Benedetto, C.
AU - Brundu, B.
AU - Facchinetti, F.
AU - Nappi, G.
PY - 2004/9
Y1 - 2004/9
N2 - Aim of this study was to determine whether menstrual attacks differ from non-menstrual attacks (NMA) as regards clinical features or response to abortive treatment in women affected by menstrually related migraine (MRM) referred to tertiary care centres. Sixty-four women with MRM were enrolled in a 2-month diary study Perimenstrual attacks were split into three groups - premenstrual (PMA), menstrual (MA) and late menstrual (LMA) - and compared to nonmenstrual ones. Perimenstrual attacks were significantly longer than NMA. No other migraine attack features were found to differ between the various phases of the cycle. Migraine work-related disability was significantly greater in PMA and MA than in NMA. Acute attack treatment was less effective in perimenstrual attacks. Pain-free at 2 h after dosage was achieved in 13.5% of MA (OR 0.41; 95% CI 0.22, 0.76) vs. 32.9% of NMA. We concluded that, in MRM, perimenstrual attacks are longer and less responsive to acute attack treatment than NMA.
AB - Aim of this study was to determine whether menstrual attacks differ from non-menstrual attacks (NMA) as regards clinical features or response to abortive treatment in women affected by menstrually related migraine (MRM) referred to tertiary care centres. Sixty-four women with MRM were enrolled in a 2-month diary study Perimenstrual attacks were split into three groups - premenstrual (PMA), menstrual (MA) and late menstrual (LMA) - and compared to nonmenstrual ones. Perimenstrual attacks were significantly longer than NMA. No other migraine attack features were found to differ between the various phases of the cycle. Migraine work-related disability was significantly greater in PMA and MA than in NMA. Acute attack treatment was less effective in perimenstrual attacks. Pain-free at 2 h after dosage was achieved in 13.5% of MA (OR 0.41; 95% CI 0.22, 0.76) vs. 32.9% of NMA. We concluded that, in MRM, perimenstrual attacks are longer and less responsive to acute attack treatment than NMA.
KW - Acute attack treatment
KW - Menstrual cycle
KW - Menstrually related migraine
KW - Migraine without aura
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U2 - 10.1111/j.1468-2982.2004.00741.x
DO - 10.1111/j.1468-2982.2004.00741.x
M3 - Article
C2 - 15315526
AN - SCOPUS:4444356861
VL - 24
SP - 707
EP - 716
JO - Cephalalgia
JF - Cephalalgia
SN - 0333-1024
IS - 9
ER -