Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women

C. Nardelli; L. Iaffaldano; M. Ferrigno; G. Labruna; G. M. Maruotti; F. Quaglia; V. Capobianco; R. Di Noto; L. Del Vecchio; P. Martinelli; L. Pastore; L. Sacchetti

doi:10.1038/ijo.2013.121

Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women

C. Nardelli, L. Iaffaldano, M. Ferrigno, G. Labruna, G. M. Maruotti, F. Quaglia, V. Capobianco, R. Di Noto, L. Del Vecchio, P. Martinelli, L. Pastore, L. Sacchetti

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Abstract

Maternal obesity and nutrient excess in utero increase the risk of future metabolic diseases. The mechanisms underlying this process are poorly understood, but probably include genetic, epigenetic alterations and changes in fetal nutrient supply. We have studied the microRNA (miRNA) expression profile in amnion from obese and control women at delivery to investigate if a specific miRNA signature is associated with obesity. The expression profile of 365 human miRNAs was evaluated with the TaqMan Array in amnion from 10 obese and 5 control (prepregnancy body mass index (BMI) >30 and

Original language	English
Pages (from-to)	466-469
Number of pages	4
Journal	International Journal of Obesity
Volume	38
Issue number	3
DOIs	https://doi.org/10.1038/ijo.2013.121
Publication status	Published - 2014

Keywords

miRNA
pathway
pregnancy

ASJC Scopus subject areas

Medicine (miscellaneous)
Nutrition and Dietetics
Endocrinology, Diabetes and Metabolism
Medicine(all)

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10.1038/ijo.2013.121

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Nardelli, C., Iaffaldano, L., Ferrigno, M., Labruna, G., Maruotti, G. M., Quaglia, F., Capobianco, V., Di Noto, R., Del Vecchio, L., Martinelli, P., Pastore, L., & Sacchetti, L. (2014). Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women. International Journal of Obesity, 38(3), 466-469. https://doi.org/10.1038/ijo.2013.121

Nardelli, C, Iaffaldano, L, Ferrigno, M, Labruna, G, Maruotti, GM, Quaglia, F, Capobianco, V, Di Noto, R, Del Vecchio, L, Martinelli, P, Pastore, L & Sacchetti, L 2014, 'Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women', International Journal of Obesity, vol. 38, no. 3, pp. 466-469. https://doi.org/10.1038/ijo.2013.121

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AU - Ferrigno, M.

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AU - Maruotti, G. M.

AU - Quaglia, F.

AU - Capobianco, V.

AU - Di Noto, R.

AU - Del Vecchio, L.

AU - Martinelli, P.

AU - Pastore, L.

AU - Sacchetti, L.

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Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women

Abstract

Keywords

ASJC Scopus subject areas

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