Abstract
Maternal obesity and nutrient excess in utero increase the risk of future metabolic diseases. The mechanisms underlying this process are poorly understood, but probably include genetic, epigenetic alterations and changes in fetal nutrient supply. We have studied the microRNA (miRNA) expression profile in amnion from obese and control women at delivery to investigate if a specific miRNA signature is associated with obesity. The expression profile of 365 human miRNAs was evaluated with the TaqMan Array in amnion from 10 obese and 5 control (prepregnancy body mass index (BMI) >30 and
| Original language | English |
|---|---|
| Pages (from-to) | 466-469 |
| Number of pages | 4 |
| Journal | International Journal of Obesity |
| Volume | 38 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- miRNA
- pathway
- pregnancy
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Endocrinology, Diabetes and Metabolism
- Medicine(all)
Cite this
Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women. / Nardelli, C.; Iaffaldano, L.; Ferrigno, M.; Labruna, G.; Maruotti, G. M.; Quaglia, F.; Capobianco, V.; Di Noto, R.; Del Vecchio, L.; Martinelli, P.; Pastore, L.; Sacchetti, L.
In: International Journal of Obesity, Vol. 38, No. 3, 2014, p. 466-469.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women
AU - Nardelli, C.
AU - Iaffaldano, L.
AU - Ferrigno, M.
AU - Labruna, G.
AU - Maruotti, G. M.
AU - Quaglia, F.
AU - Capobianco, V.
AU - Di Noto, R.
AU - Del Vecchio, L.
AU - Martinelli, P.
AU - Pastore, L.
AU - Sacchetti, L.
PY - 2014
Y1 - 2014
N2 - Maternal obesity and nutrient excess in utero increase the risk of future metabolic diseases. The mechanisms underlying this process are poorly understood, but probably include genetic, epigenetic alterations and changes in fetal nutrient supply. We have studied the microRNA (miRNA) expression profile in amnion from obese and control women at delivery to investigate if a specific miRNA signature is associated with obesity. The expression profile of 365 human miRNAs was evaluated with the TaqMan Array in amnion from 10 obese and 5 control (prepregnancy body mass index (BMI) >30 and
AB - Maternal obesity and nutrient excess in utero increase the risk of future metabolic diseases. The mechanisms underlying this process are poorly understood, but probably include genetic, epigenetic alterations and changes in fetal nutrient supply. We have studied the microRNA (miRNA) expression profile in amnion from obese and control women at delivery to investigate if a specific miRNA signature is associated with obesity. The expression profile of 365 human miRNAs was evaluated with the TaqMan Array in amnion from 10 obese and 5 control (prepregnancy body mass index (BMI) >30 and
KW - miRNA
KW - pathway
KW - pregnancy
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UR - http://www.scopus.com/inward/citedby.url?scp=84896314336&partnerID=8YFLogxK
U2 - 10.1038/ijo.2013.121
DO - 10.1038/ijo.2013.121
M3 - Article
VL - 38
SP - 466
EP - 469
JO - International Journal of Obesity
JF - International Journal of Obesity
SN - 0307-0565
IS - 3
ER -