Abstract
Fourteen mycobacterial strains isolated from pulmonary samples of independent patients in the state of Para´ (Brazil), and three strains isolated in Italy, were characterized using a polyphasic approach. Thorough genetic investigation, including whole-genome sequencing, demonstrated that the strains belong to the M. simiae complex, being most closely related to Mycobacterium interjectum. For 14 of the strains, evidence emerged supporting their inclusion in a previously unreported species of the genus Mycobacterium, for which the name Mycobacterium paraense sp. nov. is proposed (type strain, IEC26T5DSM 46749T5CCUG 66121T). The novel species is characterized by slow growth, unpigmented or pale yellow scotochromogenic colonies, and a HPLC mycolic acid profile different from other known mycobacteria. In different genetic regions, high sequence microheterogeneity was detected.
| Original language | English |
|---|---|
| Pages (from-to) | 656-662 |
| Number of pages | 7 |
| Journal | International Journal of Systematic and Evolutionary Microbiology |
| Volume | 65 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2015 |
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ASJC Scopus subject areas
- Microbiology
- Ecology, Evolution, Behavior and Systematics
- Medicine(all)
Cite this
Characterization of 17 strains belonging to the mycobacterium simiae complex and description of mycobacterium paraense sp. Nov. / Fusco Da Costa, Ana R.; Fedrizzi, Tarcisio; Lopes, Maria L.; Pecorari, Monica; Oliveira Da Costa, Wana L.; Giacobazzi, Elisabetta; Da Costa Bahia, Jeann R.; De Sanctis, Veronica; Batista Lima, Karla V.; Bertorelli, Roberto; Grottola, Antonella; Fabio, Anna; Mariottini, Alessandro; Ferretti, Pamela; Di Leva, Francesca; Serpini, Giulia Fregni; Tagliazucchi, Sara; Rumpianesi, Fabio; Jousson, Olivier; Segata, Nicola; Tortoli, Enrico.
In: International Journal of Systematic and Evolutionary Microbiology, Vol. 65, No. 2, 2015, p. 656-662.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characterization of 17 strains belonging to the mycobacterium simiae complex and description of mycobacterium paraense sp. Nov.
AU - Fusco Da Costa, Ana R.
AU - Fedrizzi, Tarcisio
AU - Lopes, Maria L.
AU - Pecorari, Monica
AU - Oliveira Da Costa, Wana L.
AU - Giacobazzi, Elisabetta
AU - Da Costa Bahia, Jeann R.
AU - De Sanctis, Veronica
AU - Batista Lima, Karla V.
AU - Bertorelli, Roberto
AU - Grottola, Antonella
AU - Fabio, Anna
AU - Mariottini, Alessandro
AU - Ferretti, Pamela
AU - Di Leva, Francesca
AU - Serpini, Giulia Fregni
AU - Tagliazucchi, Sara
AU - Rumpianesi, Fabio
AU - Jousson, Olivier
AU - Segata, Nicola
AU - Tortoli, Enrico
PY - 2015
Y1 - 2015
N2 - Fourteen mycobacterial strains isolated from pulmonary samples of independent patients in the state of Para´ (Brazil), and three strains isolated in Italy, were characterized using a polyphasic approach. Thorough genetic investigation, including whole-genome sequencing, demonstrated that the strains belong to the M. simiae complex, being most closely related to Mycobacterium interjectum. For 14 of the strains, evidence emerged supporting their inclusion in a previously unreported species of the genus Mycobacterium, for which the name Mycobacterium paraense sp. nov. is proposed (type strain, IEC26T5DSM 46749T5CCUG 66121T). The novel species is characterized by slow growth, unpigmented or pale yellow scotochromogenic colonies, and a HPLC mycolic acid profile different from other known mycobacteria. In different genetic regions, high sequence microheterogeneity was detected.
AB - Fourteen mycobacterial strains isolated from pulmonary samples of independent patients in the state of Para´ (Brazil), and three strains isolated in Italy, were characterized using a polyphasic approach. Thorough genetic investigation, including whole-genome sequencing, demonstrated that the strains belong to the M. simiae complex, being most closely related to Mycobacterium interjectum. For 14 of the strains, evidence emerged supporting their inclusion in a previously unreported species of the genus Mycobacterium, for which the name Mycobacterium paraense sp. nov. is proposed (type strain, IEC26T5DSM 46749T5CCUG 66121T). The novel species is characterized by slow growth, unpigmented or pale yellow scotochromogenic colonies, and a HPLC mycolic acid profile different from other known mycobacteria. In different genetic regions, high sequence microheterogeneity was detected.
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UR - http://www.scopus.com/inward/citedby.url?scp=84927173590&partnerID=8YFLogxK
U2 - 10.1099/ijs.0.068395-0
DO - 10.1099/ijs.0.068395-0
M3 - Article
VL - 65
SP - 656
EP - 662
JO - International Journal of Systematic and Evolutionary Microbiology
JF - International Journal of Systematic and Evolutionary Microbiology
SN - 1466-5026
IS - 2
ER -