Characterization of 17 strains belonging to the mycobacterium simiae complex and description of mycobacterium paraense sp. Nov.

Ana R. Fusco Da Costa, Tarcisio Fedrizzi, Maria L. Lopes, Monica Pecorari, Wana L. Oliveira Da Costa, Elisabetta Giacobazzi, Jeann R. Da Costa Bahia, Veronica De Sanctis, Karla V. Batista Lima, Roberto Bertorelli, Antonella Grottola, Anna Fabio, Alessandro Mariottini, Pamela Ferretti, Francesca Di Leva, Giulia Fregni Serpini, Sara Tagliazucchi, Fabio Rumpianesi, Olivier Jousson, Nicola Segata & 1 others Enrico Tortoli

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Fourteen mycobacterial strains isolated from pulmonary samples of independent patients in the state of Para´ (Brazil), and three strains isolated in Italy, were characterized using a polyphasic approach. Thorough genetic investigation, including whole-genome sequencing, demonstrated that the strains belong to the M. simiae complex, being most closely related to Mycobacterium interjectum. For 14 of the strains, evidence emerged supporting their inclusion in a previously unreported species of the genus Mycobacterium, for which the name Mycobacterium paraense sp. nov. is proposed (type strain, IEC26T5DSM 46749T5CCUG 66121T). The novel species is characterized by slow growth, unpigmented or pale yellow scotochromogenic colonies, and a HPLC mycolic acid profile different from other known mycobacteria. In different genetic regions, high sequence microheterogeneity was detected.

Original languageEnglish
Pages (from-to)656-662
Number of pages7
JournalInternational Journal of Systematic and Evolutionary Microbiology
Volume65
Issue number2
DOIs
Publication statusPublished - 2015

Fingerprint

Mycobacterium simiae
Mycobacterium
Mycobacterium interjectum
genome
Mycolic Acids
acid
Brazil
Italy
Names
High Pressure Liquid Chromatography
Genome
Lung
lungs
Growth
new species
acids

ASJC Scopus subject areas

  • Microbiology
  • Ecology, Evolution, Behavior and Systematics
  • Medicine(all)

Cite this

Characterization of 17 strains belonging to the mycobacterium simiae complex and description of mycobacterium paraense sp. Nov. / Fusco Da Costa, Ana R.; Fedrizzi, Tarcisio; Lopes, Maria L.; Pecorari, Monica; Oliveira Da Costa, Wana L.; Giacobazzi, Elisabetta; Da Costa Bahia, Jeann R.; De Sanctis, Veronica; Batista Lima, Karla V.; Bertorelli, Roberto; Grottola, Antonella; Fabio, Anna; Mariottini, Alessandro; Ferretti, Pamela; Di Leva, Francesca; Serpini, Giulia Fregni; Tagliazucchi, Sara; Rumpianesi, Fabio; Jousson, Olivier; Segata, Nicola; Tortoli, Enrico.

In: International Journal of Systematic and Evolutionary Microbiology, Vol. 65, No. 2, 2015, p. 656-662.

Research output: Contribution to journalArticle

Fusco Da Costa, AR, Fedrizzi, T, Lopes, ML, Pecorari, M, Oliveira Da Costa, WL, Giacobazzi, E, Da Costa Bahia, JR, De Sanctis, V, Batista Lima, KV, Bertorelli, R, Grottola, A, Fabio, A, Mariottini, A, Ferretti, P, Di Leva, F, Serpini, GF, Tagliazucchi, S, Rumpianesi, F, Jousson, O, Segata, N & Tortoli, E 2015, 'Characterization of 17 strains belonging to the mycobacterium simiae complex and description of mycobacterium paraense sp. Nov.', International Journal of Systematic and Evolutionary Microbiology, vol. 65, no. 2, pp. 656-662. https://doi.org/10.1099/ijs.0.068395-0
Fusco Da Costa, Ana R. ; Fedrizzi, Tarcisio ; Lopes, Maria L. ; Pecorari, Monica ; Oliveira Da Costa, Wana L. ; Giacobazzi, Elisabetta ; Da Costa Bahia, Jeann R. ; De Sanctis, Veronica ; Batista Lima, Karla V. ; Bertorelli, Roberto ; Grottola, Antonella ; Fabio, Anna ; Mariottini, Alessandro ; Ferretti, Pamela ; Di Leva, Francesca ; Serpini, Giulia Fregni ; Tagliazucchi, Sara ; Rumpianesi, Fabio ; Jousson, Olivier ; Segata, Nicola ; Tortoli, Enrico. / Characterization of 17 strains belonging to the mycobacterium simiae complex and description of mycobacterium paraense sp. Nov. In: International Journal of Systematic and Evolutionary Microbiology. 2015 ; Vol. 65, No. 2. pp. 656-662.
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AU - Jousson, Olivier

AU - Segata, Nicola

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