Abstract
We report the identification of a novel DRB3*02 using sequence-based typing (SBT). This new allele, officially named DRB3*0217, was detected while performing HLA high resolution typing of a bone marrow recipient and his siblings. DNA sequencing demonstrated the presence of a nucleotide substitution in exon 2 at position 199 where a C was substituted by a T. This point mutation at codon 67 (CTC→TTC) has resulted in an amino acid substitution from Leucine to Phenylalanine.
Original language | English |
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Pages (from-to) | 189-190 |
Number of pages | 2 |
Journal | Tissue Antigens |
Volume | 60 |
Issue number | 2 |
DOIs | |
Publication status | Published - Aug 1 2002 |
Keywords
- HLA-DRB3
- SBT
ASJC Scopus subject areas
- Cell Biology
- Immunology