Characterization of a new HLA-DRB3 allele, DRB3*0217, by direct sequencing

S. Frison, E. Longhi, F. Poli, A. Espadas De Arias, M. Scalamogna

Research output: Contribution to journalArticlepeer-review


We report the identification of a novel DRB3*02 using sequence-based typing (SBT). This new allele, officially named DRB3*0217, was detected while performing HLA high resolution typing of a bone marrow recipient and his siblings. DNA sequencing demonstrated the presence of a nucleotide substitution in exon 2 at position 199 where a C was substituted by a T. This point mutation at codon 67 (CTC→TTC) has resulted in an amino acid substitution from Leucine to Phenylalanine.

Original languageEnglish
Pages (from-to)189-190
Number of pages2
JournalTissue Antigens
Issue number2
Publication statusPublished - Aug 1 2002


  • HLA-DRB3
  • SBT

ASJC Scopus subject areas

  • Cell Biology
  • Immunology


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