Characterization of adenomas and metastases in the adrenals

comparison between spin-echo sequences and Gd-DTPA enhanced dynamic studies

Ettore Squillaci, Antonello Vidiri, Marcello Crecco, Federico Maspes, Ezio Fanucci, Maria Luisa Grandinetti, Giovanni Simonetti

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Nineteen patients with adrenal masses (9 metastases and 10 adenomas) were studied with magnetic resonance spin-echo sequences and with dynamic perfusion with gradient-echo (GE) sequences after gadolinium diethylenetriamine-pentaacetic acid injection. In studies following Gd-DTPA injection, sequential imaging during suspended respiration was obtained. Signal intensities of adrenal masses and retroperitonel fat were measured in the region of interest. The relative signal intensities of lesion and fat were determined and compared in dynamic contrast-enhanced studies. Results were tabulated and plotted in diagrams as a function of time. Sixteen lesions out of 19 were correctly classified by means of SE sequences, with an 84% diagnostic accuracy, whereas 18 out of 19 lesions were characterized by means of GE sequences, with a 95% accuracy. In the dynamic study, adenomas showed mild enhancement and quicker washout than metastases which, in turn, showed a strong enhancement and a much slower washout. The most significant values were obtained in scans taken after 10 min, where adenomas showed signal to lesion/signal to fat values lower than 1.1, whereas metastases showed much higher values in all cases.

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalEuropean Radiology
Volume3
Issue number1
DOIs
Publication statusPublished - Jan 1993

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Gadolinium DTPA
Adenoma
Neoplasm Metastasis
Fats
Pentetic Acid
Injections
Gadolinium
Respiration
Magnetic Resonance Spectroscopy
Perfusion

Keywords

  • Adrenal glands
  • Contrast media
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Characterization of adenomas and metastases in the adrenals : comparison between spin-echo sequences and Gd-DTPA enhanced dynamic studies. / Squillaci, Ettore; Vidiri, Antonello; Crecco, Marcello; Maspes, Federico; Fanucci, Ezio; Grandinetti, Maria Luisa; Simonetti, Giovanni.

In: European Radiology, Vol. 3, No. 1, 01.1993, p. 33-37.

Research output: Contribution to journalArticle

Squillaci, Ettore ; Vidiri, Antonello ; Crecco, Marcello ; Maspes, Federico ; Fanucci, Ezio ; Grandinetti, Maria Luisa ; Simonetti, Giovanni. / Characterization of adenomas and metastases in the adrenals : comparison between spin-echo sequences and Gd-DTPA enhanced dynamic studies. In: European Radiology. 1993 ; Vol. 3, No. 1. pp. 33-37.
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