Characterization of an IncL/M plasmid carrying blaOXA-48 in a Klebsiella pneumoniae strain from Italy

Paolo Gaibani, Erika Scaltriti, Chiara Benni, Stefano Pongolini, Simone Ambretti, Maria Paola Landini, Pier Luigi Viale, Maddalena Giannella, Maria Carla Re

Research output: Contribution to journalArticle

Abstract

Here we report the complete nucleotide sequence of a 49.257-bp IncL/M conjugative plasmid (pRAY) carrying the blaOXA-48 gene collected from a Klebsiella pneumoniae clinical strain isolated in Italy. The genetic environment of pRAY plasmid revealed that the blaOXA-48 gene was located within a Tn1999.2 transposon. The pRAY plasmid differed from blaOXA-48-harboring IncL/M plasmids by genetic context and size. Comparative analysis demonstrated that pRAY plasmid lacked a region of ∼15 kb carrying genes encoding proteins involved in pilus assembly and plasmid conjugative apparatus.

Original languageEnglish
Pages (from-to)284-285
Number of pages2
JournalNew Microbiologica
Volume40
Issue number4
Publication statusPublished - Oct 1 2017
Externally publishedYes

Keywords

  • Klebsiella pneumoniae
  • OXA-48
  • Plasmid

ASJC Scopus subject areas

  • Microbiology (medical)

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  • Cite this

    Gaibani, P., Scaltriti, E., Benni, C., Pongolini, S., Ambretti, S., Landini, M. P., Viale, P. L., Giannella, M., & Re, M. C. (2017). Characterization of an IncL/M plasmid carrying blaOXA-48 in a Klebsiella pneumoniae strain from Italy. New Microbiologica, 40(4), 284-285.