Abstract
A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.
| Original language | English |
|---|---|
| Pages (from-to) | 233-236 |
| Number of pages | 4 |
| Journal | Haematologica |
| Volume | 72 |
| Issue number | 3 |
| Publication status | Published - 1987 |
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ASJC Scopus subject areas
- Hematology
Cite this
Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda. / Bellotti, V.; Pavesi, F.; Merlini, G.; Zorzoli, I.; Perfetti, V.; Bergonzi, C.; Aguzzi, F.; Ascari, E.
In: Haematologica, Vol. 72, No. 3, 1987, p. 233-236.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda
AU - Bellotti, V.
AU - Pavesi, F.
AU - Merlini, G.
AU - Zorzoli, I.
AU - Perfetti, V.
AU - Bergonzi, C.
AU - Aguzzi, F.
AU - Ascari, E.
PY - 1987
Y1 - 1987
N2 - A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.
AB - A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.
UR - http://www.scopus.com/inward/record.url?scp=0023236819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023236819&partnerID=8YFLogxK
M3 - Article
C2 - 3114089
AN - SCOPUS:0023236819
VL - 72
SP - 233
EP - 236
JO - Haematologica
JF - Haematologica
SN - 0390-6078
IS - 3
ER -