Abstract
A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.
| Original language | English |
|---|---|
| Pages (from-to) | 233-236 |
| Number of pages | 4 |
| Journal | Haematologica |
| Volume | 72 |
| Issue number | 3 |
| Publication status | Published - 1987 |
Fingerprint
ASJC Scopus subject areas
- Hematology
Cite this
Bellotti, V., Pavesi, F., Merlini, G., Zorzoli, I., Perfetti, V., Bergonzi, C., Aguzzi, F., & Ascari, E. (1987). Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda. Haematologica, 72(3), 233-236.