Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda

V. Bellotti; F. Pavesi; G. Merlini; I. Zorzoli; V. Perfetti; C. Bergonzi; F. Aguzzi; E. Ascari

Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda

V. Bellotti, F. Pavesi, G. Merlini, I. Zorzoli, V. Perfetti, C. Bergonzi, F. Aguzzi, E. Ascari

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')₂ and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')₂ fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.

Original language	English
Pages (from-to)	233-236
Number of pages	4
Journal	Haematologica
Volume	72
Issue number	3
Publication status	Published - 1987

ASJC Scopus subject areas

Hematology

Cite this

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title = "Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda",

abstract = "A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.",

author = "V. Bellotti and F. Pavesi and G. Merlini and I. Zorzoli and V. Perfetti and C. Bergonzi and F. Aguzzi and E. Ascari",

year = "1987",

language = "English",

volume = "72",

pages = "233--236",

journal = "Haematologica",

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T1 - Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda

AU - Bellotti, V.

AU - Pavesi, F.

AU - Merlini, G.

AU - Zorzoli, I.

AU - Perfetti, V.

AU - Bergonzi, C.

AU - Aguzzi, F.

AU - Ascari, E.

PY - 1987

Y1 - 1987

N2 - A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.

AB - A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.

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AN - SCOPUS:0023236819

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JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 3

ER -

Characterization of anti-streptolysin 0 activity of a human monoclonal IgG lambda

Abstract

ASJC Scopus subject areas

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