Abstract
A human monoclonal component with anti-streptolysin activity (titer 1:15000) was dicovered in a patient with a monoclonal gammopathy of undetermined significance. The antibody activity was determined by a hemolysis inhibition test and immunoblotting using whole immunoglobulin and Fab,F(ab')2 and Fc fragments. The anti-streptolysin activity was found to be located in the Fab-F(ab')2 fragments and directed against a 57 Kd protein with an isoelectric point of 7.5.
Original language | English |
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Pages (from-to) | 233-236 |
Number of pages | 4 |
Journal | Haematologica |
Volume | 72 |
Issue number | 3 |
Publication status | Published - 1987 |
ASJC Scopus subject areas
- Hematology