Characterization of chimpanzee-hamster hybrids by chromosome painting

Nicoletta Archidiacono, Rosalia Marzella, Palma Finelli, Rachele Antonacci, Carol Jones, Mariano Rocchi

Research output: Contribution to journalArticle

Abstract

A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

Original languageEnglish
Pages (from-to)439-442
Number of pages4
JournalSomatic Cell and Molecular Genetics
Volume20
Issue number5
DOIs
Publication statusPublished - Sep 1994

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ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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