Characterization of chimpanzee-hamster hybrids by chromosome painting

Nicoletta Archidiacono, Rosalia Marzella, Palma Finelli, Rachele Antonacci, Carol Jones, Mariano Rocchi

Research output: Contribution to journalArticle

Abstract

A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

Original languageEnglish
Pages (from-to)439-442
Number of pages4
JournalSomatic Cell and Molecular Genetics
Volume20
Issue number5
DOIs
Publication statusPublished - Sep 1994

Fingerprint

Chromosome Painting
Pan troglodytes
Cricetinae
Chromosomes
Polymerase Chain Reaction
Hybrid Cells
Human Chromosomes
DNA

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

Cite this

Characterization of chimpanzee-hamster hybrids by chromosome painting. / Archidiacono, Nicoletta; Marzella, Rosalia; Finelli, Palma; Antonacci, Rachele; Jones, Carol; Rocchi, Mariano.

In: Somatic Cell and Molecular Genetics, Vol. 20, No. 5, 09.1994, p. 439-442.

Research output: Contribution to journalArticle

Archidiacono, N, Marzella, R, Finelli, P, Antonacci, R, Jones, C & Rocchi, M 1994, 'Characterization of chimpanzee-hamster hybrids by chromosome painting', Somatic Cell and Molecular Genetics, vol. 20, no. 5, pp. 439-442. https://doi.org/10.1007/BF02257461
Archidiacono, Nicoletta ; Marzella, Rosalia ; Finelli, Palma ; Antonacci, Rachele ; Jones, Carol ; Rocchi, Mariano. / Characterization of chimpanzee-hamster hybrids by chromosome painting. In: Somatic Cell and Molecular Genetics. 1994 ; Vol. 20, No. 5. pp. 439-442.
@article{dcb97b8f02f6490ea2ea42a2116e76b9,
title = "Characterization of chimpanzee-hamster hybrids by chromosome painting",
abstract = "A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.",
author = "Nicoletta Archidiacono and Rosalia Marzella and Palma Finelli and Rachele Antonacci and Carol Jones and Mariano Rocchi",
year = "1994",
month = "9",
doi = "10.1007/BF02257461",
language = "English",
volume = "20",
pages = "439--442",
journal = "Somatic Cell and Molecular Genetics",
issn = "0740-7750",
publisher = "Springer GmbH & Co, Auslieferungs-Gesellschaf",
number = "5",

}

TY - JOUR

T1 - Characterization of chimpanzee-hamster hybrids by chromosome painting

AU - Archidiacono, Nicoletta

AU - Marzella, Rosalia

AU - Finelli, Palma

AU - Antonacci, Rachele

AU - Jones, Carol

AU - Rocchi, Mariano

PY - 1994/9

Y1 - 1994/9

N2 - A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

AB - A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

UR - http://www.scopus.com/inward/record.url?scp=0028574703&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028574703&partnerID=8YFLogxK

U2 - 10.1007/BF02257461

DO - 10.1007/BF02257461

M3 - Article

C2 - 7825066

AN - SCOPUS:0028574703

VL - 20

SP - 439

EP - 442

JO - Somatic Cell and Molecular Genetics

JF - Somatic Cell and Molecular Genetics

SN - 0740-7750

IS - 5

ER -