Characterization of chimpanzee-hamster hybrids by chromosome painting

Nicoletta Archidiacono; Rosalia Marzella; Palma Finelli; Rachele Antonacci; Carol Jones; Mariano Rocchi

doi:10.1007/BF02257461

Characterization of chimpanzee-hamster hybrids by chromosome painting

Nicoletta Archidiacono, Rosalia Marzella, Palma Finelli, Rachele Antonacci, Carol Jones, Mariano Rocchi

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

Original language	English
Pages (from-to)	439-442
Number of pages	4
Journal	Somatic Cell and Molecular Genetics
Volume	20
Issue number	5
DOIs	https://doi.org/10.1007/BF02257461
Publication status	Published - Sep 1994

ASJC Scopus subject areas

Genetics
Cell Biology

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title = "Characterization of chimpanzee-hamster hybrids by chromosome painting",

abstract = "A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.",

author = "Nicoletta Archidiacono and Rosalia Marzella and Palma Finelli and Rachele Antonacci and Carol Jones and Mariano Rocchi",

year = "1994",

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AU - Archidiacono, Nicoletta

AU - Marzella, Rosalia

AU - Finelli, Palma

AU - Antonacci, Rachele

AU - Jones, Carol

AU - Rocchi, Mariano

PY - 1994/9

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N2 - A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

AB - A panel of chimpanzee-human somatic cell hybrids was characterized by dual Alu-PCR of the chimpanzee DNA in the hybrid and subsequent hybridization of the labeled PCR products to human and chimpanzee chromosomes. In addition to the identification of the intact chimpanzee chromosomes retained in each hybrid, chromosome fragments were identified that will be useful in regional mapping. This technique also revealed the presence of centric inversions.

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SN - 0740-7750

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Characterization of chimpanzee-hamster hybrids by chromosome painting

Abstract

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