Characterization of FOX-3, an AmpC-type plasmid-mediated β-lactamase from an italian isolate of Klebsiella oxytoca

Anna Marchese, Guillaume Arlet, Gian Carlo Schito, Philippe H. Lagrange, Alain Philippon

Research output: Contribution to journalArticlepeer-review

Abstract

Klebsiella oxytoca 1731, which showed a wide spectrum of resistance to β-lactams, including cefoxitin, was isolated in 1994 from a patient in Genoa, Italy. This strain contained a plasmid-mediated AmpC β-lactamase with a pI of 7.25. Sequencing of the corresponding DNA of K. oxytoca 1731 revealed 96 and 97% identities of the deduced amino acid sequence with FOX-1 and FOX- 2, respectively.

Original languageEnglish
Pages (from-to)464-467
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume42
Issue number2
Publication statusPublished - Feb 1998

ASJC Scopus subject areas

  • Pharmacology (medical)

Fingerprint Dive into the research topics of 'Characterization of FOX-3, an AmpC-type plasmid-mediated β-lactamase from an italian isolate of Klebsiella oxytoca'. Together they form a unique fingerprint.

Cite this