Characterization of non-type B haemophilus influenzae strains isolated from patients with invasive disease

M. Cerquetti, M. L. Ciofi Degli Atti, G. Renna, A. E. Tozzi, M. L. Garlaschi, P. Mastrantonio

Research output: Contribution to journalArticlepeer-review

Abstract

Forty-one non-type b Haemophilus influenzae isolates from cases of invasive disease were characterized. By PCR capsular genotyping, 33 nonencapsulated strains, 4 type f isolates, and 4 b- strains were identified. By pulsed-field gel electrophoresis, the nonencapsulated isolates exhibited great genetic heterogenicity, whereas the type f and the b- strains seemed to have a clonal spread. Occurrence of the hifA gene was found by PCR in 18% of the nonencapsulated, 50% of the b-, and all of the type f strains. Hemagglutinating fimbriae were generally expressed by nonencapsulated isolates when fimbrial gene hifA was present. Two nonencapsulated isolates not susceptible to ampicillin were detected; no strains were positive for β-lactamase production.

Original languageEnglish
Pages (from-to)4649-4652
Number of pages4
JournalJournal of Clinical Microbiology
Volume38
Issue number12
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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