Abstract
Two subgroup-specific monoclonal antibodies (MAb) raised in mice against group A human rotavirus were shown to react by immunoblotting with the trimeric form of VP6 of the homologous subgroup and successfully applied to development of new single-sandwich ELISA systems for rapid subgrouping of human strains. All of the 344 strains tested could be subgrouped, but for two of them prior propagation in cell cultures was required.
| Original language | English |
|---|---|
| Pages (from-to) | 315-322 |
| Number of pages | 8 |
| Journal | Archives of Virology |
| Volume | 107 |
| Issue number | 3-4 |
| DOIs | |
| Publication status | Published - Sep 1989 |
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology
- Genetics
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Gerna, G., Sarasini, A., Torsellini, M., di Matteo, A., Baldanti, F., Parea, M., & Battaglia, M. (1989). Characterization of rotavirus subgroup-specific monoclonal antibodies and use in single-sandwich ELISA systems for rapid subgrouping of human strains. Archives of Virology, 107(3-4), 315-322. https://doi.org/10.1007/BF01317927