Characterization of the antibiotic GE2270 complex by combined liquid chromatography and mass spectrometry

L. Colombo, D. Guglielmi, E. Selva, S. Stella, R. Stradi, C. Sottani, L. F. Zerilli, P. Traldi

Research output: Contribution to journalArticlepeer-review

Abstract

Components of GE2270 Complex, an antibiotic active against Gram-positive bacteria and anaerobes, were identified by continuous-flow fast-atom bombardment mass spectrometry and by combined liquid chromatography and mass spectrometry under electrospray and thermospray ionization conditions. Electrospray ionization seems to be the most suitable technique for the routine analysis of crude extracts of antibiotics from fermentation broths.

Original languageEnglish
Pages (from-to)409-412
Number of pages4
JournalRapid Communications in Mass Spectrometry
Volume10
Issue number4
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

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