Abstract
An apparently healthy 43-year-old man was submitted to cardiological evaluation for sport activity. Two-dimensional echocardiography led to suspicion of noncompaction deformity, later confirmed by magnetic resonance imaging (MRI), left ventricular catheterization and endomyocardial biopsies. To exclude life-threatening arrhythmias, the patient was submitted to an electrophysiological study and to a real-time three-dimensional electroanatomic reconstruction of left ventricle. The electroanatomic map revealed extensive area of electrical abnormalities. Extent and localization of scar areas mostly corresponded to the areas of enhancement observed at MRI.The present report is the first on electroanatomic substrate evaluation in a noncompaction left ventricle. Our findings show that ventricular noncompaction is characterized by electrical abnormalities including low voltage and scar areas, mainly related to the presence and extent of myocardial fibrosis rather than noncompacted myocardium. Electroanatomic mapping may contribute to detect and quantify fibrotic areas in patients presenting this rare cardiomyopathy.
| Original language | English |
|---|---|
| Pages (from-to) | 636-638 |
| Number of pages | 3 |
| Journal | Journal of Cardiovascular Medicine |
| Volume | 9 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2008 |
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Keywords
- Arrhythmic risk
- Electroanatomic mapping
- Noncompaction cardiomyopathy
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Characterization of the electroanatomic substrate in a case of noncompaction left ventricle. / Casella, Michela; Pieroni, Maurizio; Russo, Antonio Dello; Pennestrì, Faustino; Meduri, Agostino; Natale, Luigi; Bellocci, Fulvio; Crea, Filippo.
In: Journal of Cardiovascular Medicine, Vol. 9, No. 6, 06.2008, p. 636-638.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Characterization of the electroanatomic substrate in a case of noncompaction left ventricle
AU - Casella, Michela
AU - Pieroni, Maurizio
AU - Russo, Antonio Dello
AU - Pennestrì, Faustino
AU - Meduri, Agostino
AU - Natale, Luigi
AU - Bellocci, Fulvio
AU - Crea, Filippo
PY - 2008/6
Y1 - 2008/6
N2 - An apparently healthy 43-year-old man was submitted to cardiological evaluation for sport activity. Two-dimensional echocardiography led to suspicion of noncompaction deformity, later confirmed by magnetic resonance imaging (MRI), left ventricular catheterization and endomyocardial biopsies. To exclude life-threatening arrhythmias, the patient was submitted to an electrophysiological study and to a real-time three-dimensional electroanatomic reconstruction of left ventricle. The electroanatomic map revealed extensive area of electrical abnormalities. Extent and localization of scar areas mostly corresponded to the areas of enhancement observed at MRI.The present report is the first on electroanatomic substrate evaluation in a noncompaction left ventricle. Our findings show that ventricular noncompaction is characterized by electrical abnormalities including low voltage and scar areas, mainly related to the presence and extent of myocardial fibrosis rather than noncompacted myocardium. Electroanatomic mapping may contribute to detect and quantify fibrotic areas in patients presenting this rare cardiomyopathy.
AB - An apparently healthy 43-year-old man was submitted to cardiological evaluation for sport activity. Two-dimensional echocardiography led to suspicion of noncompaction deformity, later confirmed by magnetic resonance imaging (MRI), left ventricular catheterization and endomyocardial biopsies. To exclude life-threatening arrhythmias, the patient was submitted to an electrophysiological study and to a real-time three-dimensional electroanatomic reconstruction of left ventricle. The electroanatomic map revealed extensive area of electrical abnormalities. Extent and localization of scar areas mostly corresponded to the areas of enhancement observed at MRI.The present report is the first on electroanatomic substrate evaluation in a noncompaction left ventricle. Our findings show that ventricular noncompaction is characterized by electrical abnormalities including low voltage and scar areas, mainly related to the presence and extent of myocardial fibrosis rather than noncompacted myocardium. Electroanatomic mapping may contribute to detect and quantify fibrotic areas in patients presenting this rare cardiomyopathy.
KW - Arrhythmic risk
KW - Electroanatomic mapping
KW - Noncompaction cardiomyopathy
UR - http://www.scopus.com/inward/record.url?scp=43549092081&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43549092081&partnerID=8YFLogxK
U2 - 10.2459/JCM.0b013e3282f394b9
DO - 10.2459/JCM.0b013e3282f394b9
M3 - Article
C2 - 18475136
AN - SCOPUS:43549092081
VL - 9
SP - 636
EP - 638
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 6
ER -