TY - JOUR
T1 - Chemokines and their receptors in asthma and chronic obstructive pulmonary disease
AU - Panina-Bordignon, Paola
AU - D'Ambrosio, Daniele
PY - 2003/3
Y1 - 2003/3
N2 - Recruitment of inflammatory cells into the airways is a critical event that triggers and sustains the clinical manifestations of asthma and chronic obstructive pulmonary disease. Since the identification of the family of chemotactic cytokines, known as chemokines, as critical regulators of cell trafficking in the immune system, these molecules have come to the center stage in the field of inflammation and immunity. The goal of this article will be to summarize the recent developments in our understanding of the complex role that chemokines play in the pathogenesis of asthma and COPD.
AB - Recruitment of inflammatory cells into the airways is a critical event that triggers and sustains the clinical manifestations of asthma and chronic obstructive pulmonary disease. Since the identification of the family of chemotactic cytokines, known as chemokines, as critical regulators of cell trafficking in the immune system, these molecules have come to the center stage in the field of inflammation and immunity. The goal of this article will be to summarize the recent developments in our understanding of the complex role that chemokines play in the pathogenesis of asthma and COPD.
UR - http://www.scopus.com/inward/record.url?scp=0037363770&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037363770&partnerID=8YFLogxK
U2 - 10.1097/00063198-200303000-00003
DO - 10.1097/00063198-200303000-00003
M3 - Article
C2 - 12574689
AN - SCOPUS:0037363770
VL - 9
SP - 104
EP - 110
JO - Current Opinion in Pulmonary Medicine
JF - Current Opinion in Pulmonary Medicine
SN - 1070-5287
IS - 2
ER -