Chemokines and their receptors in asthma and chronic obstructive pulmonary disease

Paola Panina-Bordignon, Daniele D'Ambrosio

Research output: Contribution to journalArticlepeer-review

Abstract

Recruitment of inflammatory cells into the airways is a critical event that triggers and sustains the clinical manifestations of asthma and chronic obstructive pulmonary disease. Since the identification of the family of chemotactic cytokines, known as chemokines, as critical regulators of cell trafficking in the immune system, these molecules have come to the center stage in the field of inflammation and immunity. The goal of this article will be to summarize the recent developments in our understanding of the complex role that chemokines play in the pathogenesis of asthma and COPD.

Original languageEnglish
Pages (from-to)104-110
Number of pages7
JournalCurrent Opinion in Pulmonary Medicine
Volume9
Issue number2
DOIs
Publication statusPublished - Mar 2003

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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