TY - JOUR
T1 - Chemotherapy and skin reactions
AU - Fabbrocini, Gabriella
AU - Cameli, Norma
AU - Romano, Maria Concetta
AU - Mariano, Maria
AU - Panariello, Luigia
AU - Bianca, Dario
AU - Monfrecola, Giuseppe
PY - 2012
Y1 - 2012
N2 - Background: New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a worsening of patients quality of life. Appropriate management of skin toxicity associated with chemotherapic agents is therefore necessary for suitable drug administration and to improve quality of life and clinical outcomes. Methods: We have clinically examined 100 patients affected by cancer, determining type, frequency, treatment, and evolution of side effects related to chemotherapy. Results: The prevalent cutaneous side effects in patients undergoing chemotherapy are skin rash, xerosis, pruritus, paronychia, hair abnormality, and mucositis. The clinical cases are reported in detail. Conclusion: Oncological therapies have become more selective and have low systemic toxicity because of their high specificity, but cutaneous side effects are common and may worsen the quality of life of these patients.
AB - Background: New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a worsening of patients quality of life. Appropriate management of skin toxicity associated with chemotherapic agents is therefore necessary for suitable drug administration and to improve quality of life and clinical outcomes. Methods: We have clinically examined 100 patients affected by cancer, determining type, frequency, treatment, and evolution of side effects related to chemotherapy. Results: The prevalent cutaneous side effects in patients undergoing chemotherapy are skin rash, xerosis, pruritus, paronychia, hair abnormality, and mucositis. The clinical cases are reported in detail. Conclusion: Oncological therapies have become more selective and have low systemic toxicity because of their high specificity, but cutaneous side effects are common and may worsen the quality of life of these patients.
KW - Anti-EGF
KW - Chemotherapy
KW - Follicular rash
KW - Paronychia
KW - Skin toxicity
KW - Xerosis
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U2 - 10.1186/1756-9966-31-50
DO - 10.1186/1756-9966-31-50
M3 - Article
C2 - 22640460
AN - SCOPUS:84861443537
VL - 31
JO - Journal of Experimental and Clinical Cancer Research
JF - Journal of Experimental and Clinical Cancer Research
SN - 0392-9078
IS - 1
M1 - 50
ER -