Chemotherapy for malignant gliomas of the brain: a review of ten-years experience

P. Paoletti, G. Butti, R. Knerich, P. Gaetani, R. Assietti

Research output: Contribution to journalArticlepeer-review


In recent years, there has been a great improvement in the knowledge of the biological aspects of malignant gliomas of the brain. Conversely, there has been an increase of interest in the multimodal treatment of these tumours. In this review, we have analyzed the results of the several reports which have appeared in the literature that deal with the chemotherapeutic treatment of malignant gliomas. Furthermore, some areas of biological investigation that could have an impact on pharmacological therapy are discussed.

Original languageEnglish
Pages (from-to)35-46
Number of pages12
JournalActa Neurochirurgica
Issue number1-2
Publication statusPublished - Mar 1990


  • Brain neoplasm
  • chemotherapy
  • malignant glioma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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