Chemo/tomotherapy stereotactic body radiation therapy (chemo/SBRT) for the salvage treatment of esophageal carcinoma following trimodality therapy: A case report

Davide Adriano Santeufemia, Salvatore Tumolo, Antonino De Paoli, Giovanni Lo Re, Gianni Boz, Gian Maria Miolo, Tanja Baresic, Stefano Maria Massimiliano Basso, Roberto Innocente

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background. Esophageal cancer (EC) patients presenting a local recurrence following trimodality therapy (chemoradiaton and surgery) have limited palliative treatment options when the three major modalities of therapy have been exhausted. In addition, some patients experience a local recurrence or develop a metachronous cancer in a previously irradiated site, without evidence of systemic disease. For these patients there is a potential for cure, although the risk of further distant recurrences remains high. Case report. We report of a successful concomitant chemo/SBRT treatment in a case of locally advanced metachronous squamous cervical EC, which was diagnosed in a patient previously treated with trimodality therapy for a squamous tonsillar carcinoma. Result. Chemo/SBRT seems to be a reasonable salvage option for patients without distant metastases who have exhausted standard therapies. Conclusions. Our experience also suggests that a concomitant chemo/SBRT treatment appears to be either feasible or effective and chemo/SBRT can be considered also in selected patients affected by EC with squamous histology and with neoplastic infiltration of the trachea.

Original languageEnglish
JournalTumori
Volume98
Issue number5
DOIs
Publication statusPublished - Sep 2012

Fingerprint

Salvage Therapy
Radiotherapy
Carcinoma
Esophageal Neoplasms
Recurrence
Therapeutics
Trachea
Palliative Care
Uterine Cervical Neoplasms
Squamous Cell Carcinoma
Histology
Neoplasm Metastasis
Neoplasms

Keywords

  • Esophageal cancer
  • Recurrence
  • Tomotherapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Chemo/tomotherapy stereotactic body radiation therapy (chemo/SBRT) for the salvage treatment of esophageal carcinoma following trimodality therapy : A case report. / Santeufemia, Davide Adriano; Tumolo, Salvatore; De Paoli, Antonino; Lo Re, Giovanni; Boz, Gianni; Miolo, Gian Maria; Baresic, Tanja; Basso, Stefano Maria Massimiliano; Innocente, Roberto.

In: Tumori, Vol. 98, No. 5, 09.2012.

Research output: Contribution to journalArticle

Santeufemia, Davide Adriano ; Tumolo, Salvatore ; De Paoli, Antonino ; Lo Re, Giovanni ; Boz, Gianni ; Miolo, Gian Maria ; Baresic, Tanja ; Basso, Stefano Maria Massimiliano ; Innocente, Roberto. / Chemo/tomotherapy stereotactic body radiation therapy (chemo/SBRT) for the salvage treatment of esophageal carcinoma following trimodality therapy : A case report. In: Tumori. 2012 ; Vol. 98, No. 5.
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AU - De Paoli, Antonino

AU - Lo Re, Giovanni

AU - Boz, Gianni

AU - Miolo, Gian Maria

AU - Baresic, Tanja

AU - Basso, Stefano Maria Massimiliano

AU - Innocente, Roberto

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