Chemo/tomotherapy stereotactic body radiation therapy (chemo/SBRT) for the salvage treatment of esophageal carcinoma following trimodality therapy: A case report

Davide Adriano Santeufemia, Salvatore Tumolo, Antonino De Paoli, Giovanni Lo Re, Gianni Boz, Gian Maria Miolo, Tanja Baresic, Stefano Maria Massimiliano Basso, Roberto Innocente

Research output: Contribution to journalArticle

Abstract

Background. Esophageal cancer (EC) patients presenting a local recurrence following trimodality therapy (chemoradiaton and surgery) have limited palliative treatment options when the three major modalities of therapy have been exhausted. In addition, some patients experience a local recurrence or develop a metachronous cancer in a previously irradiated site, without evidence of systemic disease. For these patients there is a potential for cure, although the risk of further distant recurrences remains high. Case report. We report of a successful concomitant chemo/SBRT treatment in a case of locally advanced metachronous squamous cervical EC, which was diagnosed in a patient previously treated with trimodality therapy for a squamous tonsillar carcinoma. Result. Chemo/SBRT seems to be a reasonable salvage option for patients without distant metastases who have exhausted standard therapies. Conclusions. Our experience also suggests that a concomitant chemo/SBRT treatment appears to be either feasible or effective and chemo/SBRT can be considered also in selected patients affected by EC with squamous histology and with neoplastic infiltration of the trachea.

Original languageEnglish
JournalTumori
Volume98
Issue number5
DOIs
Publication statusPublished - Sep 2012

Keywords

  • Esophageal cancer
  • Recurrence
  • Tomotherapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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