Chest wall mechanics during pressure support ventilation

Andrea Aliverti, Eleonora Carlesso, Raffaele Dellacà, Paolo Pelosi, Davide Chiumello, Antonio Pedotti, Luciano Gattinoni

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Introduction: During pressure support ventilation (PSV) a part of the breathing pattern is controlled by the patient, and synchronization of respiratory muscle action and the resulting chest wall kinematics is a valid indicator of the patient's adaptation to the ventilator. The aim of the present study was to analyze the effects of different PSV settings on ventilatory pattern, total and compartmental chest wall kinematics and dynamics, muscle pressures and work of breathing in patients with acute lung injury. Method: In nine patients four different levels of PSV (5, 10, 15 and 25 cmH2O) were randomly applied with the same level of positive end-expiratory pressure (10 cmH2O). Flow, airway opening, and oesophageal and gastric pressures were measured, and volume variations for the entire chest wall, the ribcage and abdominal compartments were recorded by opto-electronic plethysmography. The pressure and the work generated by the diaphragm, rib cage and abdominal muscles were determined using dynamic pressure-volume loops in the various phases of each respiratory cycle: pre-triggering, post-triggering with the patient's effort combining with the action of the ventilator, pressurization and expiration. The complete breathing pattern was measured and correlated with chest wall kinematics and dynamics. Results: At the various levels of pressure support applied, minute ventilation was constant, with large variations in breathing frequency/ tidal volume ratio. At pressure support levels below 15 cmH2O the following increased: the pressure developed by the inspiratory muscles, the contribution of the rib cage compartment to the total tidal volume, the phase shift between rib cage and abdominal compartments, the post-inspiratory action of the inspiratory rib cage muscles, and the expiratory muscle activity. Conclusion: During PSV, the ventilatory pattern is very different at different levels of pressure support; in patients with acute lung injury pressure support greater than 10 cmH2O permits homogeneous recruitment of respiratory muscles, with resulting synchronous thoraco-abdominal expansion.

Original languageEnglish
Article numberR54
JournalCritical Care
Volume10
Issue number2
DOIs
Publication statusPublished - Mar 31 2006

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Thoracic Wall
Mechanics
Ventilation
Pressure
Biomechanical Phenomena
Muscles
Respiration
Respiratory Muscles
Acute Lung Injury
Tidal Volume
Mechanical Ventilators
Work of Breathing
Abdominal Muscles
Plethysmography
Positive-Pressure Respiration
Diaphragm
Stomach
Rib Cage

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Medicine(all)

Cite this

Aliverti, A., Carlesso, E., Dellacà, R., Pelosi, P., Chiumello, D., Pedotti, A., & Gattinoni, L. (2006). Chest wall mechanics during pressure support ventilation. Critical Care, 10(2), [R54]. https://doi.org/10.1186/cc4867

Chest wall mechanics during pressure support ventilation. / Aliverti, Andrea; Carlesso, Eleonora; Dellacà, Raffaele; Pelosi, Paolo; Chiumello, Davide; Pedotti, Antonio; Gattinoni, Luciano.

In: Critical Care, Vol. 10, No. 2, R54, 31.03.2006.

Research output: Contribution to journalArticle

Aliverti, A, Carlesso, E, Dellacà, R, Pelosi, P, Chiumello, D, Pedotti, A & Gattinoni, L 2006, 'Chest wall mechanics during pressure support ventilation', Critical Care, vol. 10, no. 2, R54. https://doi.org/10.1186/cc4867
Aliverti A, Carlesso E, Dellacà R, Pelosi P, Chiumello D, Pedotti A et al. Chest wall mechanics during pressure support ventilation. Critical Care. 2006 Mar 31;10(2). R54. https://doi.org/10.1186/cc4867
Aliverti, Andrea ; Carlesso, Eleonora ; Dellacà, Raffaele ; Pelosi, Paolo ; Chiumello, Davide ; Pedotti, Antonio ; Gattinoni, Luciano. / Chest wall mechanics during pressure support ventilation. In: Critical Care. 2006 ; Vol. 10, No. 2.
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