Chest X-ray survey in the follow-up of breast cancer patients

S. Ciatto, P. Pacini, C. Andreoli, S. Cecchini, A. Iossa, G. Grazzini, F. Buranelli, T. Campa, A. Costa, A. Magni, M. Pizzichetta

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Abstract

The authors report on 182 cases of intrathoracic metastasis (ITM = lung, pleura or mediastinum) observed as first single recurrences in the course of the follow-up of patients treated for primary breast cancer. ITM were detected on standard two-views chest X-ray (CXR) at regular follow-up visits and in absence of subjective symptoms (102 A cases) or in the interval between two consecutive planned controls because of the onset of subjective symptoms (80 S cases). The average disease-free interval since primary treatment was significantly shorter in A with respect to S cases (40.3 vs. 28.5 months, P <0.001) as a consequence of the early detection achieved by CXR survey. On the contrary, prognosis was not influenced by ITM early diagnosis as the 10-year survival since primary treatment did not differ significantly between A or S cases (12% vs. 10%, P = 0.68). Results were confirmed on multivariate (Cox's) analysis, adjusting for potential confounders such as age or nodal status. Periodic CXR survey looks a very questionable policy as it does not seem to have any favourable impact on prognosis. Its routine use in breast cancer patients should thus be carefully reconsidered.

Original languageEnglish
Pages (from-to)102-103
Number of pages2
JournalBritish Journal of Cancer
Volume60
Issue number1
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Ciatto, S., Pacini, P., Andreoli, C., Cecchini, S., Iossa, A., Grazzini, G., Buranelli, F., Campa, T., Costa, A., Magni, A., & Pizzichetta, M. (1989). Chest X-ray survey in the follow-up of breast cancer patients. British Journal of Cancer, 60(1), 102-103.