Chiari 2 without spinal dysraphism: Does it blow a hole in the pathogenesis?

Valentina Citton, Irene Toldo, Laura Balao, Andrea Pettenazzo, Enzo Emanuelli, Stefano Sartori, Milena Calderone, Renzo Manara

Research output: Contribution to journalArticle

Abstract

Chiari malformation type 2 is characterized by hindbrain protrusion and a constellation of supratentorial malformations. Chiari malformation type 2 is thought to be causally related to myelomeningocele due to intrauterine cerebrospinal fluid overdrainage. This relationship is so strong that it has become a rule. A 14-year-old girl affected by mental retardation, spastic triparesis, and epilepsy is presented. Brain magnetic resonance imaging disclosed a severe Chiari malformation type 2, whereas spine magnetic resonance imaging was unremarkable. The authors discuss previous literature describing rare cases of Chiari malformation type 2 without open spinal dysraphism and the relevance of concomitant, sometimes overlooked, neuroimaging findings, underlying how exceptions might be hurdles but might also eventually strengthen the rules.

Original languageEnglish
Pages (from-to)536-539
Number of pages4
JournalJournal of Child Neurology
Volume27
Issue number4
DOIs
Publication statusPublished - Apr 2012

Fingerprint

Arnold-Chiari Malformation
Spinal Dysraphism
Magnetic Resonance Imaging
Meningomyelocele
Rhombencephalon
Muscle Spasticity
Neuroimaging
Intellectual Disability
Cerebrospinal Fluid
Epilepsy
Spine
Brain

Keywords

  • Chiari malformation type 2
  • epilepsy
  • myelomeningocele
  • spinal dysraphism

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

Citton, V., Toldo, I., Balao, L., Pettenazzo, A., Emanuelli, E., Sartori, S., ... Manara, R. (2012). Chiari 2 without spinal dysraphism: Does it blow a hole in the pathogenesis? Journal of Child Neurology, 27(4), 536-539. https://doi.org/10.1177/0883073811435239

Chiari 2 without spinal dysraphism : Does it blow a hole in the pathogenesis? / Citton, Valentina; Toldo, Irene; Balao, Laura; Pettenazzo, Andrea; Emanuelli, Enzo; Sartori, Stefano; Calderone, Milena; Manara, Renzo.

In: Journal of Child Neurology, Vol. 27, No. 4, 04.2012, p. 536-539.

Research output: Contribution to journalArticle

Citton, V, Toldo, I, Balao, L, Pettenazzo, A, Emanuelli, E, Sartori, S, Calderone, M & Manara, R 2012, 'Chiari 2 without spinal dysraphism: Does it blow a hole in the pathogenesis?', Journal of Child Neurology, vol. 27, no. 4, pp. 536-539. https://doi.org/10.1177/0883073811435239
Citton V, Toldo I, Balao L, Pettenazzo A, Emanuelli E, Sartori S et al. Chiari 2 without spinal dysraphism: Does it blow a hole in the pathogenesis? Journal of Child Neurology. 2012 Apr;27(4):536-539. https://doi.org/10.1177/0883073811435239
Citton, Valentina ; Toldo, Irene ; Balao, Laura ; Pettenazzo, Andrea ; Emanuelli, Enzo ; Sartori, Stefano ; Calderone, Milena ; Manara, Renzo. / Chiari 2 without spinal dysraphism : Does it blow a hole in the pathogenesis?. In: Journal of Child Neurology. 2012 ; Vol. 27, No. 4. pp. 536-539.
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