TY - JOUR
T1 - Childhood adversity, early-onset depressive/anxiety disorders, and adult-onset asthma
AU - Scott, Kate M.
AU - Korff, Michael Von
AU - Alonso, Jordi
AU - Angermeyer, Matthias C.
AU - Benjet, Corina
AU - Bruffaerts, Ronny
AU - Girolamo, Giovanni De
AU - Haro, Josep Maria
AU - Kessler, Ronald C.
AU - Kovess, Viviane
AU - Ono, Yutaka
AU - Ormel, Johan
AU - Posada-Villa, Jose
PY - 2008/11
Y1 - 2008/11
N2 - Objectives: To investigate a) whether childhood adversity predicts adult-onset asthma; b) whether early-onset depressive/anxiety disorders predict adult-onset asthma; and c) whether childhood adversity and early-onset depressive/anxiety disorders predict adult-onset asthma independently of each other. Previous research has suggested, but not established, that childhood adversity may predict adult-onset asthma and, moreover, that the association between mental disorders and asthma may be a function of shared risk factors, such as childhood adversity. Methods: Ten cross-sectional population surveys of household-residing adults (=18 years, n = 18,303) assessed mental disorders with the Composite International Diagnostic Interview (CIDI 3.0) as part of the World Mental Health surveys. Assessment of a range of childhood family adversities was included. Asthma was ascertained by self-report of lifetime diagnosis and age of diagnosis. Survival analyses calculated hazard ratios (HRs) for risk of adult-onset (>age 20 years) asthma as a function of number and type of childhood adversities and early-onset (
AB - Objectives: To investigate a) whether childhood adversity predicts adult-onset asthma; b) whether early-onset depressive/anxiety disorders predict adult-onset asthma; and c) whether childhood adversity and early-onset depressive/anxiety disorders predict adult-onset asthma independently of each other. Previous research has suggested, but not established, that childhood adversity may predict adult-onset asthma and, moreover, that the association between mental disorders and asthma may be a function of shared risk factors, such as childhood adversity. Methods: Ten cross-sectional population surveys of household-residing adults (=18 years, n = 18,303) assessed mental disorders with the Composite International Diagnostic Interview (CIDI 3.0) as part of the World Mental Health surveys. Assessment of a range of childhood family adversities was included. Asthma was ascertained by self-report of lifetime diagnosis and age of diagnosis. Survival analyses calculated hazard ratios (HRs) for risk of adult-onset (>age 20 years) asthma as a function of number and type of childhood adversities and early-onset (
KW - Anxiety disorders
KW - Asthma
KW - Childhood adversity
KW - Comorbidity
KW - Depressive disorders
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U2 - 10.1097/PSY.0b013e318187a2fb
DO - 10.1097/PSY.0b013e318187a2fb
M3 - Article
C2 - 18941133
AN - SCOPUS:59849093363
VL - 70
SP - 1035
EP - 1043
JO - Psychosomatic Medicine
JF - Psychosomatic Medicine
SN - 0033-3174
IS - 9
ER -