Childhood generalized specific phobia as an early marker of internalizing psychopathology across the lifespan: results from the World Mental Health Surveys

Ymkje Anna de Vries, Ali Al-Hamzawi, Jordi Alonso, Guilherme Borges, Ronny Bruffaerts, Brendan Bunting, José Miguel Caldas-de-Almeida, Alfredo H Cia, Giovanni De Girolamo, Rumyana V Dinolova, Oluyomi Esan, Silvia Florescu, Oye Gureje, Josep Maria Haro, Chiyi Hu, Elie G Karam, Aimee Karam, Norito Kawakami, Andrzej Kiejna, Viviane Kovess-MasfetySing Lee, Zeina Mneimneh, Fernando Navarro-Mateu, Marina Piazza, Kate Scott, Margreet Ten Have, Yolanda Torres, Maria Carmen Viana, Ronald C Kessler, Peter de Jonge, WHO World Mental Health Survey Collaborators

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Specific phobia (SP) is a relatively common disorder associated with high levels of psychiatric comorbidity. Because of its early onset, SP may be a useful early marker of internalizing psychopathology, especially if generalized to multiple situations. This study aimed to evaluate the association of childhood generalized SP with comorbid internalizing disorders. METHODS: We conducted retrospective analyses of the cross-sectional population-based World Mental Health Surveys using the Composite International Diagnostic Interview. Outcomes were lifetime prevalence, age of onset, and persistence of internalizing disorders; past-month disability; lifetime suicidality; and 12-month serious mental illness. Logistic and linear regressions were used to assess the association of these outcomes with the number of subtypes of childhood-onset (
Original languageEnglish
Article number101
Number of pages1
JournalBMC Medicine
Volume17
Issue number1
DOIs
Publication statusPublished - May 24 2019

Keywords

  • *Comorbidity
  • *Early markers
  • *Internalizing disorders
  • *Specific phobia
  • *Suicidality
  • Adolescent
  • Adult
  • Age of Onset
  • Aged
  • Aging/psychology
  • Biomarkers/analysis
  • Child
  • Cross-Sectional Studies
  • Early Diagnosis
  • Female
  • Global Health/statistics & numerical data
  • Health Surveys
  • Humans
  • Longevity
  • Male
  • Mental Disorders/diagnosis/*epidemiology
  • Mental Health
  • Middle Aged
  • Phobic Disorders/*diagnosis/*epidemiology
  • Prevalence
  • Psychopathology
  • Retrospective Studies
  • Young Adult

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