Abstract
We review 30 cases of pediatric systemic lupus erythematosus followed over an 8-year period at our institution. The female to male ratio was 3.3:1; the age at diagnosis ranged between 3.5 and 16 years. On first admission, renal involvement was detected in the majority of the patients, as assessed by laboratory findings and/or clinical manifestations. Other frequently observed symptoms were fever, skin rashes, arthralgias and/or arthritis and serositis. All of the patients were treated with corticosteroids and most of them also received immunosuppressive drugs in order to control disease activity. Two patients were lost to the follow-up, five died and only one of the 23 evaluable patients is off therapy after a median follow-up of 5 years. This study confirms that pediatric systemic lupus erythematosus is a very aggressive disease.
| Original language | English |
|---|---|
| Pages (from-to) | 425-430 |
| Number of pages | 6 |
| Journal | Clinical and Experimental Rheumatology |
| Volume | 9 |
| Issue number | 4 |
| Publication status | Published - 1991 |
Fingerprint
ASJC Scopus subject areas
- Immunology
- Rheumatology
Cite this
Childhood systemic lupus erythematosus : A review of 30 cases. / Buoncompagni, A.; Barbano, G. C.; Pistoia, V.; Fasce, L.; Micalizzi, C.; Gusmano, R.; Cordone, G.; Cottafava, F.; Mori, P. G.; Franchini, E.; Ferrarini, M.; Borrone, C.
In: Clinical and Experimental Rheumatology, Vol. 9, No. 4, 1991, p. 425-430.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Childhood systemic lupus erythematosus
T2 - A review of 30 cases
AU - Buoncompagni, A.
AU - Barbano, G. C.
AU - Pistoia, V.
AU - Fasce, L.
AU - Micalizzi, C.
AU - Gusmano, R.
AU - Cordone, G.
AU - Cottafava, F.
AU - Mori, P. G.
AU - Franchini, E.
AU - Ferrarini, M.
AU - Borrone, C.
PY - 1991
Y1 - 1991
N2 - We review 30 cases of pediatric systemic lupus erythematosus followed over an 8-year period at our institution. The female to male ratio was 3.3:1; the age at diagnosis ranged between 3.5 and 16 years. On first admission, renal involvement was detected in the majority of the patients, as assessed by laboratory findings and/or clinical manifestations. Other frequently observed symptoms were fever, skin rashes, arthralgias and/or arthritis and serositis. All of the patients were treated with corticosteroids and most of them also received immunosuppressive drugs in order to control disease activity. Two patients were lost to the follow-up, five died and only one of the 23 evaluable patients is off therapy after a median follow-up of 5 years. This study confirms that pediatric systemic lupus erythematosus is a very aggressive disease.
AB - We review 30 cases of pediatric systemic lupus erythematosus followed over an 8-year period at our institution. The female to male ratio was 3.3:1; the age at diagnosis ranged between 3.5 and 16 years. On first admission, renal involvement was detected in the majority of the patients, as assessed by laboratory findings and/or clinical manifestations. Other frequently observed symptoms were fever, skin rashes, arthralgias and/or arthritis and serositis. All of the patients were treated with corticosteroids and most of them also received immunosuppressive drugs in order to control disease activity. Two patients were lost to the follow-up, five died and only one of the 23 evaluable patients is off therapy after a median follow-up of 5 years. This study confirms that pediatric systemic lupus erythematosus is a very aggressive disease.
UR - http://www.scopus.com/inward/record.url?scp=0025875767&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025875767&partnerID=8YFLogxK
M3 - Article
C2 - 1934695
AN - SCOPUS:0025875767
VL - 9
SP - 425
EP - 430
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
SN - 0392-856X
IS - 4
ER -