Children and COVID-19: Microbiological and immunological insights

Danilo Buonsenso, Michela Sali, Davide Pata, Cristina De Rose, Maurizio Sanguinetti, Piero Valentini, Giovanni Delogu

Research output: Contribution to journalReview articlepeer-review


Since its first description in China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide being declared a pandemic by the World Health Organization. More than 10.3 million people have been infected and more than 506 000 people died. However, SARS-CoV-2 had a lower impact on the pediatric population. Only about 1% to 2% of infected people are children and few deaths under the age of 14 are described so far. In this article, we discuss microbiological and immunological characteristics of SARS-CoV-2 infection in children highlighting the main differences from adult SARS-CoV-2 infection.

Original languageEnglish
Pages (from-to)2547-2555
Number of pages9
JournalPediatric Pulmonology
Issue number10
Publication statusPublished - Oct 1 2020


  • children
  • COVID-19
  • immunology
  • novel coronavirus
  • SARS-CoV-2

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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