Children of a lesser god or miracles? An emotional and behavioural profile of children born to mothers on dialysis in Italy: A multicentre nationwide study 2000-12

Giorgina Barbara Piccoli, Valentina Postorino, Gianfranca Cabiddu, Sara Ghiotto, Gabriella Guzzo, Simona Roggero, Eleonora Manca, Rosalba Puddu, Francesca Meloni, Rossella Attini, Paolo Moi, Stefania Maxia, Antonio Piga, Luigi Mazzone, Antonello Pani, Maurizio Postorino, Santina Castellino, Giuseppe Gernone, Bruna Guida, Santo CalabriaMarco Galliani, Gianfranco Manisco, Massimo Di Tullio, Luigi Vernaglione, Maria Grazia Chiappini, Emanuela Proietti, Stefano Saffiotti, Concetta Gangeni, Chiara Brunati, Alberto Montoli, Ciro Esposito, Giovanni Montagna, Salvatore Tata, Paolo Romano, Ottavio Amatruda, Paolo Cervini, Erika Casiraghi, Paolo Fabbrini, Federico Pieruzzi, Attilio Di Benedetto, Giuseppina Alfisi, Marco Heidempergher, Monique Buskermolen, Alessandro Leveque, Valerie Autuly, Francesco Giofrè, Giovanni Alati, Luigi Lombardi, Mara Riccio, Ivano Riccio, Kidney and Pregnancy Study Group of the 'Italian Society of Nephrology'

Research output: Contribution to journalArticle

Abstract

Background Pregnancy on dialysis is increasingly being reported. This study evaluates the behavioural profile of the children of mothers on dialysis and the parental stress their mothers undergo when compared with a group of mothers affected by a different chronic disease (microcythaemia) and a group of healthy control mothers. Methods Between 2000 and 2012, 23 on-dialysis mothers gave birth to 24 live-born children in Italy (23 pregnancies, 1 twin pregnancy, one of the twins deceased soon after delivery); of these, 16 mothers and 1 father (whose wife died before the inquiry) were included in the study (1 mother had died and the father was unavailable; 2 were not asked to participate because their children had died and 3 were unavailable; children: median age: 8.5, min-max: 2-13 years). Twenty-three mothers affected by transfusion-dependent microcythaemia or drepanocitosis (31 pregnancies, 32 children) and 35 healthy mothers (35 pregnancies, 35 children; median age of the children: 7, min-max: 1-13 years) were recruited as controls. All filled in the validated questionnaires: 'Child Behaviour Checklist' (CBCL) and the 'Parental Stress Index-Short Form' (PSI-SF). Results The results of the CBCL questionnaire were similar for mothers on dialysis and healthy controls except for pervasive developmental problems, which were significantly higher in the dialysis group, while microcythaemia mothers reported higher emotional and behavioural problems in their children in 8 CBCL sub-scales. Two/16 children in the dialysis and 3/32 in the microcythaemia group had pathological profiles, as assessed by T-scores (p: ns). PSI-SF indicated a normal degree of parental stress in microcythaemia subjects and healthy controls, while mothers on dialysis declared significantly lower stress, suggesting a defensive response in order to minimize problems, stress or negativity in their relationship with their child. Conclusions According to the present analysis, the emotional and behavioural outcome is normal in most of the children from on-dialysis mothers. A 'positive defence' in the dialysis mothers should be kept in mind when tailoring psychological support for this medical miracle.

Original languageEnglish
Pages (from-to)1193-1202
Number of pages10
JournalNephrology Dialysis Transplantation
Volume30
Issue number7
DOIs
Publication statusPublished - Jul 1 2015

Keywords

  • depression
  • dialysis
  • ESRD
  • microcythaemia
  • pregnancy
  • stress

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

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    Piccoli, G. B., Postorino, V., Cabiddu, G., Ghiotto, S., Guzzo, G., Roggero, S., Manca, E., Puddu, R., Meloni, F., Attini, R., Moi, P., Maxia, S., Piga, A., Mazzone, L., Pani, A., Postorino, M., Castellino, S., Gernone, G., Guida, B., ... Kidney and Pregnancy Study Group of the 'Italian Society of Nephrology' (2015). Children of a lesser god or miracles? An emotional and behavioural profile of children born to mothers on dialysis in Italy: A multicentre nationwide study 2000-12. Nephrology Dialysis Transplantation, 30(7), 1193-1202. https://doi.org/10.1093/ndt/gfv127