Le formulazioni di collutori contenenti clorexidina influenzano la vitalità del biofilm di Streptococcus mutans: uno studio in vitro

OBJECTIVES To evaluate in vitro the influence of mouthwashes with different formulations on the development of S. mutans biofilm. MATERIALS AND METHODS A monospecific biofilm of S. mutans was obtained in a bioreactor under continuous flow conditions for 20 h. Biofilms were exposed for 2 min to mouthwashes containing chlorhexidine (CHX), sodium hyaluronate and PVP-VA polymer. After additional 4 h of incubation, the amount of viable adherent biomass on polystyrene surfaces was assessed by plate count. RESULTS All the tested solutions showed antibiofilm activity, with varying effectiveness. CONCLUSIONS The antibiofilm efficacy of a mouthwash depends not only on the active principle but also on the association with other compounds not necessarily possessing antibiofilm activity.